Hestermann Elke, Schreve Kristiaan, Vandenheever David
Multi-Modality Medical Imaging (M3i) Group, Faculty of Science and Technology, Technical Medical Centre, University of Twente, P.O. Box 217, 7500 AE Enschede, The Netherlands.
Department of Mechanical and Mechatronics Engineering, University of Stellenbosch, Joubert Street, Stellenbosch 7602, South Africa.
Sensors (Basel). 2024 Nov 22;24(23):7471. doi: 10.3390/s24237471.
This study presents the development of a wireless in-ear EEG device designed to monitor brain activity during sleep and deliver auditory stimuli aimed at enhancing deep sleep. The device records EEG signals and plays a combined auditory stimulus consisting of autonomous sensory meridian response (ASMR) and 3 Hz binaural beats at a 60:30 dB ratio, intended to promote delta wave activity and non-rapid eye movement (NREM) stage 3 sleep. Fifteen participants completed this study, which included two consecutive nights: a baseline night and a testing night. Participants were divided into an experimental group, which received the combined ASMR and binaural beat stimulus, and a control group, which received only ASMR. The combined stimulus was delivered upon entering NREM stage 2 and replaced by ASMR when NREM stage 3 was reached. Results showed that the experimental group experienced an increase in NREM 3 sleep, a decrease in NREM 2 sleep, and a slight increase in NREM 3 latency compared to the baseline night. Although the findings are promising, further testing with a larger sample size is required to confirm the device's potential to enhance sleep quality and promote delta activity in the brain.
本研究介绍了一种无线入耳式脑电图设备的研发情况,该设备旨在监测睡眠期间的大脑活动,并提供旨在增强深度睡眠的听觉刺激。该设备记录脑电图信号,并播放一种组合听觉刺激,该刺激由自主感觉经络反应(ASMR)和3赫兹双耳节拍组成,比例为60:30分贝,旨在促进δ波活动和非快速眼动(NREM)第3阶段睡眠。15名参与者完成了这项研究,其中包括连续两个晚上:一个基线夜晚和一个测试夜晚。参与者被分为实验组和对照组,实验组接受ASMR和双耳节拍的组合刺激,对照组只接受ASMR。组合刺激在进入NREM第2阶段时给予,当达到NREM第3阶段时被ASMR取代。结果显示,与基线夜晚相比,实验组的NREM第3阶段睡眠增加,NREM第2阶段睡眠减少,NREM第3阶段潜伏期略有增加。尽管研究结果很有前景,但需要用更大的样本量进行进一步测试,以确认该设备在提高睡眠质量和促进大脑δ活动方面的潜力。