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一例以腰痛为首发症状的真菌性心内膜炎病例报告。

A case report of fungal endocarditis presenting with low back pain as the initial symptom.

作者信息

Xu Haixia, Zhang Hang, Wu Jiacheng, Jin Libo

机构信息

Department of Cardiovascular Surgery, Shaoxing People's Hospital, Shaoxing, Zhejiang Province, China.

出版信息

Medicine (Baltimore). 2024 Dec 13;103(50):e40962. doi: 10.1097/MD.0000000000040962.

Abstract

RATIONALE

Fungal endocarditis (FE) is a rare form of infective endocarditis. Compared to bacterial endocarditis, FE develops more slowly and insidiously, with nonspecific clinical manifestations, making diagnosis more challenging. Cases presenting with low back pain as the initial symptom are exceedingly rare, leading to a high risk of misdiagnosis or delayed diagnosis.

PATIENT CONCERNS

A 61-year-old male was admitted due to recurrent low back pain accompanied by fever for 2 months. He had no history of invasive procedures or immunosuppressive therapy.

DIAGNOSES

The patient was diagnosed with FE.

INTERVENTIONS

The patient underwent surgical treatment, during which the excrescence was removed, and mitral valve replacement was performed. Postoperatively, he received a full course of antifungal therapy.

OUTCOMES

Postoperatively, the patient experienced relief from low back pain and was afebrile. He was discharged after completing antifungal treatment and, upon follow-up after 1 year, had no recurrence of low back pain.

LESSONS

In this case, the patient initially presented with low back pain, which, despite the presence of fever and other signs of infection, did not readily suggest a cardiac etiology. This case highlights the importance of not being misled by superficial symptoms and underscores the need for comprehensive and accurate physical examinations and targeted investigations for proper diagnosis.

摘要

理论依据

真菌性心内膜炎(FE)是感染性心内膜炎的一种罕见形式。与细菌性心内膜炎相比,FE发展更为缓慢且隐匿,临床表现不具特异性,这使得诊断更具挑战性。以腰痛为首发症状的病例极为罕见,导致误诊或延迟诊断的风险很高。

患者情况

一名61岁男性因反复腰痛伴发热2个月入院。他没有侵入性操作或免疫抑制治疗史。

诊断

该患者被诊断为FE。

干预措施

患者接受了手术治疗,术中切除赘生物并进行了二尖瓣置换。术后,他接受了全程抗真菌治疗。

结果

术后,患者腰痛缓解且无发热。完成抗真菌治疗后出院,1年随访时腰痛未复发。

经验教训

在本病例中,患者最初表现为腰痛,尽管存在发热和其他感染迹象,但并未轻易提示心脏病因。该病例强调了不被表面症状误导的重要性,并强调了进行全面准确的体格检查和针对性检查以进行正确诊断的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ece8/11651508/185c84b20973/medi-103-e40962-g001.jpg

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