Ma Jie, Rui Zong, Zou Yuhui, Qin Zhizhen, Zhao Zhenyu, Zhang Yanyang, Mao Zhiqi, Bai Hongmin, Zhang Jianning
PLA Medical School, Beijing, 100853, PR China.
Department of Neurosurgery, Chinese PLA General Hospital, Beijing, 100853, PR China.
Heliyon. 2024 Oct 11;10(23):e39072. doi: 10.1016/j.heliyon.2024.e39072. eCollection 2024 Dec 15.
This study investigates the effects of occipital lobe tumors on visual processing and the role of brain-computer interface (BCI) technologies in post-surgical visual rehabilitation. Through a combination of pre-surgical functional magnetic resonance imaging (fMRI) and Diffusion Tensor Imaging (DTI), intra-operative direct cortical stimulation (DCS) and Electrocorticography (ECoG), and post-surgical BCI interventions, we provide insight into the complex dynamics between occipital lobe tumors and visual function. Our results highlight a discrepancy between clinical assessments of visual field damage and the patient's reported visual experiences, suggesting a residual functional capacity within the damaged occipital regions. Additionally, the absence of expected visual phenomena during surgery and the promising outcomes from BCI-driven rehabilitation underscore the complexity of visual processing and the potential of technology-enhanced rehabilitation strategies. This work emphasizes the need for an interdisciplinary approach in developing effective treatments for visual impairments related to brain tumors, illustrating the significant implications for neurosurgical practices and the advancement of rehabilitation sciences.
本研究调查枕叶肿瘤对视觉处理的影响以及脑机接口(BCI)技术在术后视觉康复中的作用。通过术前功能磁共振成像(fMRI)和弥散张量成像(DTI)、术中直接皮层刺激(DCS)和皮层脑电图(ECoG)以及术后BCI干预相结合的方法,我们深入了解了枕叶肿瘤与视觉功能之间的复杂动态关系。我们的结果突出了视野损伤的临床评估与患者报告的视觉体验之间的差异,表明受损枕叶区域内存在残余功能能力。此外,手术期间未出现预期的视觉现象以及BCI驱动的康复取得的有前景的结果强调了视觉处理的复杂性以及技术增强康复策略的潜力。这项工作强调了在开发针对与脑肿瘤相关的视觉障碍的有效治疗方法时采用跨学科方法的必要性,说明了这对神经外科实践和康复科学进展的重大意义。