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麻疹暴发的经济负担:消除麻疹后时代一个中等收入国家的疾病成本研究

Economic burden of measles outbreaks: a cost-of-illness study in a middle-income country in the post-elimination era.

作者信息

de Soárez Patrícia Coelho, Rozman Luciana Martins, Fonseca Taiane Siraisi, Borsari Pietro Rodrigo, Percio Jadher, Barrera Lely Stella Guzmán, Sartori Ana Marli Christovam

机构信息

Universidade de São Paulo São Paulo Brazil Universidade de São Paulo, São Paulo, Brazil.

Universidade de Brasília Brasília Brazil Universidade de Brasília, Brasília, Brazil.

出版信息

Rev Panam Salud Publica. 2024 Dec 16;48:e103. doi: 10.26633/RPSP.2024.103. eCollection 2024.

DOI:10.26633/RPSP.2024.103
PMID:39687243
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11648058/
Abstract

OBJECTIVE

To estimate the direct costs associated with the diagnosis, treatment, and control of measles cases in Brazil from 2018 to 2020.

METHODS

This cost-of-illness study utilized a prevalence-based approach, considering direct costs incurred by the Brazilian Public Health System (SUS) related to measles outbreaks, including costs of inpatient care, outpatient care, and laboratory tests, as well as measles-containing vaccines and laboratory tests (viral isolation) used for outbreak control. Costs are presented in 2020 US dollars. Univariate and bivariate sensitivity analyses were performed.

RESULTS

There were 36 236 confirmed measles cases from 2018 to 2020. The estimated outbreaks cost was USD 107 960 122, with the cost per case ranging from USD 2 601 to USD 3 654 (mean USD 2 979).

CONCLUSIONS

These findings highlight the substantial economic burden imposed by measles outbreaks in Brazil and emphasize the importance of measles prevention and control measures. Policymakers and public health authorities can use these results to plan and allocate resources, to mitigate the economic impact of future outbreaks.

摘要

目的

估算2018年至2020年巴西麻疹病例诊断、治疗及控制相关的直接成本。

方法

本疾病成本研究采用基于患病率的方法,考虑巴西公共卫生系统(SUS)因麻疹疫情产生的直接成本,包括住院护理、门诊护理及实验室检测成本,以及用于疫情控制的含麻疹疫苗和实验室检测(病毒分离)成本。成本以2020年美元呈现。进行了单变量和双变量敏感性分析。

结果

2018年至2020年有36236例确诊麻疹病例。估计疫情成本为107960122美元,每例成本在2601美元至3654美元之间(平均2979美元)。

结论

这些发现凸显了巴西麻疹疫情造成的巨大经济负担,并强调了麻疹预防和控制措施的重要性。政策制定者和公共卫生当局可利用这些结果来规划和分配资源,以减轻未来疫情的经济影响。

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The methodological quality of economic evaluations of measles outbreaks: A systematic review of cost-of-illness studies.麻疹暴发经济评估的方法学质量:成本效益研究的系统评价。
Vaccine. 2023 Feb 10;41(7):1319-1332. doi: 10.1016/j.vaccine.2023.01.015. Epub 2023 Jan 25.
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