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通过美洲区域监测与重新核实委员会维持麻疹和风疹消除成果

Sustaining measles and rubella elimination through the Regional Monitoring and Re-Verification Commission in the Americas.

作者信息

Andrus Jon K, Santos Jose I, Evans Gilbert Tracy, Siqueira Marilda, Gentile Angela, Boshell Jorge, Reef Susan

机构信息

Department of Global Health Milken Institute School of Public Health George Washington University Washington, D.C. United States of America Department of Global Health, Milken Institute School of Public Health, George Washington University, Washington, D.C., United States of America.

School of Medicine Universidad Nacional Autónoma de Mexico Mexico City Mexico School of Medicine, Universidad Nacional Autónoma de Mexico, Mexico City, Mexico.

出版信息

Rev Panam Salud Publica. 2024 Dec 16;48:e93. doi: 10.26633/RPSP.2024.93. eCollection 2024.

Abstract

The elimination of endemic rubella and measles transmission in the Region of the Americas was verified by the Pan American Health Organization's (PAHO) Regional Verification Commission in 2015 and 2016, respectively. Upon achieving this success, this Commission was disbanded. Shortly afterwards, the Region faced challenges in the post-elimination era, notably responding to and stopping transmission of imported measles cases. As a result, Brazil and Venezuela (Bolivarian Republic of) lost their measles-free status in February 2019 and July 2018, respectively. These events spurred PAHO to form the Measles and Rubella Elimination Regional Monitoring and Re-Verification Commission (MRE-RVC) focused on re-verifying these two countries and providing intensive evaluations of all countries in their efforts to sustain elimination. The MRE-RVC was tasked with advocacy to help revitalize the necessary political commitment to provide sufficient resources to sustain measles and rubella elimination in the Americas. Maintaining measles and rubella elimination in the Region is important, despite the challenges such as the global circulation of measles and rubella viruses elsewhere. This paper outlines the activities of the MRE-RVC to address the challenges and the lessons learnt, and provides insight on sustaining the gains. The main reasons to sustain efforts are: measles vaccine saves more lives than any other vaccine; congenital rubella syndrome is still the leading cause of infectious disease birth defects in the world; and measles vaccination performance remains an indicator of national capacity to maintain health security and a timely response to future infectious disease threats. A global target for measles and rubella elimination is crucial.

摘要

2015年和2016年,泛美卫生组织(PAHO)的区域核实委员会分别核实了美洲区域风疹和麻疹的地方性传播已被消除。取得这一成功后,该委员会解散。此后不久,该区域在消除疾病后的时代面临挑战,特别是应对和阻止输入性麻疹病例的传播。结果,巴西和委内瑞拉玻利瓦尔共和国分别于2019年2月和2018年7月失去了无麻疹状态。这些事件促使泛美卫生组织成立了麻疹和风疹消除区域监测与重新核实委员会(MRE-RVC),专注于重新核实这两个国家,并对所有国家维持消除工作的努力进行深入评估。MRE-RVC的任务是进行宣传,以帮助重振必要的政治承诺,为在美洲维持麻疹和风疹消除工作提供足够资源。尽管存在诸如麻疹和风疹病毒在其他地方全球传播等挑战,但在该区域维持麻疹和风疹消除工作仍然很重要。本文概述了MRE-RVC应对挑战的活动及经验教训,并提供了维持成果的见解。持续努力的主要原因是:麻疹疫苗比任何其他疫苗挽救的生命更多;先天性风疹综合征仍然是世界上传染病导致出生缺陷的主要原因;麻疹疫苗接种表现仍然是国家维持卫生安全和及时应对未来传染病威胁能力的一个指标。制定消除麻疹和风疹的全球目标至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0f22/11648175/7c59c76cb197/rpsp-48-e93-Figure1.jpg

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