Patrick Regan E, Dickinson Rebecca A, Gregg Allison, Kaufman Jack R, Maciarz Jeremy, Merrill Julia G, Williams Loreal A, Weisenbach Sara L
Department of Neuropsychology, McLean Hospital, Belmont, MA 02478, USA.
Division of Geriatric Psychiatry, McLean Hospital, Belmont, MA 02478, USA.
J Psychiatr Brain Sci. 2024;9(6). doi: 10.20900/jpbs.20240008. Epub 2024 Nov 22.
Emotion regulation (ER), or the ability to modulate the experience and expression of emotion, is critical to adaptive functioning and is a key feature of mood disorders. At the same time, normal aging is associated with changes in ER, though the interaction of aging with the presence of a mood disorder are unclear. Here, we review what is known about ER and its underlying neural mechanisms in late life mood disorders, specifically late life depression and bipolar disorder. We also review behavioral and neuromodulation therapies that seek to reduce negative affect and improve positive affect. We conclude with recommendations for future research into the nature and mechanisms of ER and interventions targeting ER in older adults with mood disorders.
情绪调节(ER),即调节情绪体验和表达的能力,对适应性功能至关重要,是情绪障碍的一个关键特征。同时,正常衰老与情绪调节的变化有关,尽管衰老与情绪障碍存在之间的相互作用尚不清楚。在这里,我们回顾了关于晚年情绪障碍,特别是晚年抑郁症和双相情感障碍中情绪调节及其潜在神经机制的已知情况。我们还回顾了旨在减少负面影响并改善正面影响的行为和神经调节疗法。我们最后提出了针对老年人情绪障碍中情绪调节的性质和机制以及针对情绪调节的干预措施的未来研究建议。