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合成代谢类固醇诱导的纤维化的管理。

Management of Synthol-induced Fibrosis.

作者信息

Nassar Aref, Osseis Michael, Sleilati Fadi, Nasr Marwan, Abou Zeid Samer

机构信息

From the Plastic Surgery Department, Hotel Dieu de France, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.

General Surgery Department, Hotel Dieu de France, Faculty of Medicine, Saint Joseph University, Beirut, Lebanon.

出版信息

Plast Reconstr Surg Glob Open. 2024 Dec 13;12(12):e6391. doi: 10.1097/GOX.0000000000006391. eCollection 2024 Dec.

DOI:10.1097/GOX.0000000000006391
PMID:39687419
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11649267/
Abstract

Site enhancement oils, such as synthol, are sometimes used by bodybuilders to artificially increase muscle size and shape. However, these injections can lead to severe complications, including fibrosis, infections, and impaired muscle function. We report the case of a 45-year-old male patient who presented with severe fibrosis and recurrent infections in the pectoral region following synthol injections. The patient experienced several episodes of infection in the left pectoral area, which were treated with antibiotics, resulting in indurated, erythematous skin. The patient underwent surgical removal of the fibrotic tissue under general anesthesia. This case highlights the severe complications associated with synthol injections and underscores the importance of a meticulous surgical approach to manage these complications. Excision of fibrotic tissue is essential for reducing the risk of reinfection and restoring a normal appearance while carefully weighing the extent of tissue removal to avoid unnecessary damage to healthy structures. Preparing for potential blood loss and balancing the extent of tissue removal with the need to preserve normal function and appearance are crucial for successful outcomes.

摘要

诸如合成醇之类的局部增强油有时被健美运动员用于人为增大肌肉尺寸和改变肌肉形状。然而,这些注射可能导致严重并发症,包括纤维化、感染和肌肉功能受损。我们报告了一例45岁男性患者的病例,该患者在注射合成醇后胸部出现严重纤维化和反复感染。患者左侧胸部经历了数次感染,均用抗生素治疗,导致皮肤硬结、红斑。患者在全身麻醉下接受了纤维化组织的手术切除。该病例突出了与合成醇注射相关的严重并发症,并强调了采用细致的手术方法处理这些并发症的重要性。切除纤维化组织对于降低再次感染风险和恢复正常外观至关重要,同时要仔细权衡组织切除范围以避免对健康结构造成不必要的损害。为潜在的失血做好准备,并在组织切除范围与保留正常功能和外观的需求之间取得平衡,对于取得成功的结果至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09c0/11649267/ae57fde90e67/gox-12-e6391-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09c0/11649267/31e1bdd4f2ef/gox-12-e6391-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09c0/11649267/ae57fde90e67/gox-12-e6391-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09c0/11649267/31e1bdd4f2ef/gox-12-e6391-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/09c0/11649267/ae57fde90e67/gox-12-e6391-g002.jpg

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引用本文的文献

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Intramuscular synthol injections cause hypercalcemia in long-term observation: a case report study.长期观察发现肌肉注射合成类固醇导致高钙血症:一项病例报告研究。
BMC Nephrol. 2025 Aug 20;26(1):476. doi: 10.1186/s12882-025-04397-5.

本文引用的文献

1
Complications after liquid body contouring with site-enhancing oil injections.使用部位强化油注射进行液体身体塑形后的并发症。
Clin Dermatol. 2022 Sep-Oct;40(5):556-563. doi: 10.1016/j.clindermatol.2022.03.001. Epub 2022 Apr 6.
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No pain no gain: tender nodules in a competitive bodybuilder.一分耕耘一分收获:一位竞技健美运动员身上的压痛性结节
Dermatol Online J. 2018 Jul 15;24(7):13030/qt5w91h58x.
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Muscle mania: the quest for the perfect body.肌肉狂热:对完美身材的追求。
BMJ Case Rep. 2016 Dec 1;2016:bcr2016217208. doi: 10.1136/bcr-2016-217208.
4
Painful muscle fibrosis following synthol injections in a bodybuilder: a case report.一名健美运动员注射合成代谢类固醇后出现疼痛性肌肉纤维化:病例报告
J Med Case Rep. 2012 Aug 20;6:248. doi: 10.1186/1752-1947-6-248.
5
Irreversible muscle damage in bodybuilding due to long-term intramuscular oil injection.健美导致的长期肌肉内注射油引起的不可逆肌肉损伤。
Int J Sports Med. 2012 Oct;33(10):829-34. doi: 10.1055/s-0032-1311582. Epub 2012 May 16.
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[The usage of synthol in the body building].[合成代谢类固醇在健美运动中的使用]
Polim Med. 2009;39(1):63-5.
7
Compression bandage as treatment for ulcers induced by intramuscular self-injection of paraffin oil.压迫绷带治疗肌肉内自我注射石蜡油所致溃疡
Acta Derm Venereol. 2009;89(2):196-7. doi: 10.2340/00015555-0583.
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Chirurg. 2000 Nov;71(11):1370-3. doi: 10.1007/s001040051228.