Kang Minjeong, Bae Hyeona, Yu DoHyeon
College of Veterinary Medicine, Gyeongsang National University, Jinju, South Korea.
Vet Med Sci. 2025 Jan;11(1):e70168. doi: 10.1002/vms3.70168.
Hamartoma is characterized by the abnormal proliferation of cells and tissues within the originating organ. Apocrine hamartoma (AH) affecting the skin, especially in the perianal area, has not yet been reported in dogs. A 7-year-old neutered male Poodle presented with multiple perianal papules and pruritus. Histopathological examination revealed significant enlargement of the apocrine glands and ducts, accompanied by mononuclear cell infiltration that extended into the subcutis. Given the location, number, depth and extent of the lesion, CO laser ablation was chosen over surgical resection. Complete recovery was observed at the surgical site 1 month after treatment, and pruritic symptoms were markedly reduced. CO laser ablation is a relatively safe and effective palliative treatment for perianal AH in dogs.
错构瘤的特征是起源器官内的细胞和组织异常增殖。影响皮肤,尤其是肛周区域的大汗腺错构瘤(AH)在犬类中尚未见报道。一只7岁已绝育的雄性贵宾犬出现多个肛周丘疹和瘙痒症状。组织病理学检查显示大汗腺和导管显著增大,伴有单核细胞浸润并延伸至皮下组织。鉴于病变的位置、数量、深度和范围,选择CO2激光消融而非手术切除。治疗1个月后手术部位完全恢复,瘙痒症状明显减轻。CO2激光消融是治疗犬肛周AH的一种相对安全有效的姑息治疗方法。