Konstantinova Nataliia, von der Mark Claudia, De Rybel Bert
Ghent University, Department of Plant Biotechnology and Bioinformatics, Ghent, Belgium.
VIB Center for Plant Systems Biology, Ghent, Belgium.
J Exp Bot. 2025 Apr 9;76(6):1546-1552. doi: 10.1093/jxb/erae509.
The orientation of cell division is crucial for normal development of all plant organs throughout their life cycle. Despite the importance of understanding the intricate molecular mechanisms guiding this process, relatively few pathways have been characterized to date. Here we want to outline what is known about the molecular regulation guiding changes in division orientation in the root apical meristem of the model plant Arabidopsis thaliana, from the upstream transcriptional modules to the downstream executors that lead to division plane establishment. We specifically focus on the gaps in our knowledge about this highly coordinated process and propose that a new approach should be taken to characterize how changes in division orientation are controlled in more holistic detail.
细胞分裂的方向对于所有植物器官在其整个生命周期中的正常发育至关重要。尽管了解指导这一过程的复杂分子机制很重要，但迄今为止，已被表征的途径相对较少。在这里，我们想概述一下关于模式植物拟南芥根尖分生组织中指导分裂方向变化的分子调控的已知情况，从上游转录模块到导致分裂平面建立的下游执行因子。我们特别关注我们对这个高度协调过程的认识空白，并建议应采用一种新方法来更全面详细地表征分裂方向的变化是如何被控制的。
