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埃塞俄比亚提格雷州新生儿的新生儿死亡率预测因素:一项横断面研究。

Predictors of neonatal mortality among neonates in Tigray regional state, Ethiopia: A cross-sectional study.

作者信息

Gebrerufael Gebru Gebremeskel, Welegebrial Brhane Gebrehiwot, Teklezgi Mehari Gebre

机构信息

Department of Statistics, College of Natural Science, Adigrat University, Adigrat, Ethiopia.

Department of Pharmacy, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia.

出版信息

PLoS One. 2024 Dec 17;19(12):e0315400. doi: 10.1371/journal.pone.0315400. eCollection 2024.

Abstract

BACKGROUND

Since 2015, Ethiopia is committed to lowering the death rate for children under five and it is one of the countries in Sub-Saharan Africa that has accomplished the fourth Millennium Development Goal. However, in Ethiopia, neonatal death has remained a serious public health concern, with greater rates found in Tigray regional state and the predictors aren't well recognized. The goal of this study was to ascertain the prevalence of neonatal death in the Tigray regional State as well as any relevant risk factors.

METHODS

This study performed a secondary data analysis of the 2016 Ethiopia Demographic and Health Survey (EDHS) report. Information was gathered on 716 neonates who were born five years before the survey began. Risk factors for neonatal mortality were thought to include mother and neonate demographics, health, and environmental factors. The study employed multivariable logistic regression model analysis and descriptive statistics to identify significant correlates of neonatal mortality.

RESULTS

In Tigray regional state, the overall prevalence of neonatal mortality was 4.3% (95% CI: 3.06, 6.10). The multivariable logistic regression model analysis revealed that factors such as multiple birth types (AOR = 15.3, 95% CI: 3.54, 65.84), birth order (2-4) (AOR = 4.88, 95% CI: 1.52, 15.7), sex of the neonate (being male) (AOR = 3.75, 95% CI: 1.45, 9.75), home place of delivery (AOR = 7.4, 95% CI: 2.0, 27.6), and neonates born to mothers aged 20-34 years (AOR = 0.23, 95% CI: 0.087, 0.58) were significantly risk factors associated with a higher risk of neonatal mortality rate.

CONCLUSIONS

The study recognized the sex of the neonate, birth order, mother's age, place of delivery, and birth type as potential risk factors for neonatal mortality. The prevalence of neonatal mortality indicated that the neonatal mortality rate in Tigray regional state was higher than the national average. To reduce neonatal mortality, targeted interventions should focus on high-risk groups, such as mothers delivering at home and those with multiple births.

摘要

背景

自2015年以来,埃塞俄比亚致力于降低五岁以下儿童的死亡率,并且是撒哈拉以南非洲地区实现第四个千年发展目标的国家之一。然而,在埃塞俄比亚,新生儿死亡仍然是一个严重的公共卫生问题,提格雷州的发生率更高,且相关预测因素尚未得到充分认识。本研究的目的是确定提格雷州新生儿死亡的患病率以及任何相关风险因素。

方法

本研究对2016年埃塞俄比亚人口与健康调查(EDHS)报告进行了二次数据分析。收集了在调查开始前五年出生的716名新生儿的信息。新生儿死亡率的风险因素被认为包括母亲和新生儿的人口统计学、健康状况以及环境因素。该研究采用多变量逻辑回归模型分析和描述性统计来确定新生儿死亡率的显著相关因素。

结果

在提格雷州,新生儿死亡率的总体患病率为4.3%(95%置信区间:3.06,6.10)。多变量逻辑回归模型分析显示,诸如多胎类型(比值比 = 15.3,95%置信区间:3.54,65.84)、出生顺序(2 - 4)(比值比 = 4.88,95%置信区间:1.52,15.7)、新生儿性别(男性)(比值比 = 3.75,95%置信区间:1.45,9.75)、家庭分娩地点(比值比 = 7.4,95%置信区间:2.0,27.6)以及母亲年龄在20 - 34岁之间所生的新生儿(比值比 = 0.23,95%置信区间:0.087,0.58)等因素是与新生儿死亡率较高风险显著相关的危险因素。

结论

该研究确认新生儿性别、出生顺序、母亲年龄、分娩地点和出生类型为新生儿死亡的潜在风险因素。新生儿死亡率表明提格雷州的新生儿死亡率高于全国平均水平。为降低新生儿死亡率,有针对性的干预措施应聚焦于高危群体,如在家分娩的母亲和多胞胎母亲。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f3d6/11651602/263db0be6a01/pone.0315400.g001.jpg

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