da Silva Brenda Evelin Barreto, Minicozzi Pamela, Di Carlo Veronica, Ssenyonga Naomi, Khan Baloch Fatima, Matz Melissa, Coleman Michel P, Allemani Claudia, Lima Carlos Anselmo
Health Sciences Graduate Program, Federal University of Sergipe, Aracaju, Sergipe, Brazil.
Cancer Survival Group, Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, UK.
Cancer Epidemiol. 2025 Feb;94:102720. doi: 10.1016/j.canep.2024.102720. Epub 2024 Dec 16.
Ovarian cancer survival in low- and middle-income countries is lower than in high-income countries, due to disparities in healthcare access and socioeconomic factors. This study aimed to describe trends in ovarian cancer survival in Sergipe, Northeast Brazil, by histological group.
We analysed data on 948 women aged 15-99 years diagnosed with a cancer of the ovary between 1996 and 2017, in Sergipe, Brazil. One- and five-year net survival were estimated by histological group and calendar periods of diagnosis (1996-1999, 2000-2004, 2005-2009, 2010-2014, 2015-2017) using the Pohar-Perme estimator. Survival estimates were age-standardised using International Cancer Survival Standard weights.
Between 1996 and 2017, one-year and five-year net survival for ovarian cancer were 63.4 % and 37.4 %, respectively. Five-year net survival trends increased from 30.9 % (2000-2004) to 46.8 % (2015-2017). Epithelial type I tumours comprised roughly a quarter of cases, while type II tumours constituted over half. Both types exhibited similar one-year survival, ranging from 67 % to 68.5 % during 1996-2017. However, five-year net survival for type II tumours was remarkably lower at 32.5 %, compared to 52 % for type I tumours.
Despite a minor improvement in five-year net survival over the 22 years, survival for women with ovarian cancer remains unfavourable, particularly for those diagnosed with Type II epithelial tumours, which have remarkably lower five-year survival than Type I.
由于医疗保健可及性和社会经济因素的差异，低收入和中等收入国家的卵巢癌生存率低于高收入国家。本研究旨在按组织学分组描述巴西东北部塞尔希培州卵巢癌生存率的趋势。
我们分析了1996年至2017年间在巴西塞尔希培州诊断为卵巢癌的948名15 - 99岁女性的数据。使用波哈尔 - 佩尔梅估计器按组织学分组和诊断日历期（1996 - 1999年、2000 - 2004年、2005 - 2009年、2010 - 2014年、2015 - 2017年）估计1年和5年净生存率。生存率估计值使用国际癌症生存标准权重进行年龄标准化。
1996年至2017年间，卵巢癌的1年和5年净生存率分别为63.4%和37.4%。5年净生存率趋势从2000 - 2004年的30.9%上升至2015 - 2017年的46.8%。I型上皮性肿瘤约占病例的四分之一，而II型肿瘤占一半以上。两种类型在1996 - 2017年期间的1年生存率相似，范围在67%至68.5%之间。然而，II型肿瘤的5年净生存率显著较低，为32.5%，而I型肿瘤为52%。
尽管在22年中5年净生存率有小幅改善，但卵巢癌女性的生存率仍然不佳，特别是对于那些被诊断为II型上皮性肿瘤的患者，其5年生存率明显低于I型。
