Farmery S M, Owen F, Poulter M, Crow T J
Life Sci. 1985 Feb 4;36(5):473-7. doi: 10.1016/0024-3205(85)90260-7.
Cholecystokinin (CCK) binding sites were assessed in post-mortem brain membrane preparations from controls and schizophrenic patients. 125I-BH CCK33 specific binding was reduced by 40% (p less than 0.02) in the hippocampus and by 20% (p less than 0.01) in the frontal cortex of schizophrenic patients compared with controls. There were no differences in 125I-BH CCK33 binding between the two groups in the amygdala, temporal cortex or caudate nucleus.
在对照组和精神分裂症患者的死后脑膜制剂中评估胆囊收缩素（CCK）结合位点。与对照组相比，精神分裂症患者海马体中125I-BH CCK33特异性结合减少了40%（p<0.02），额叶皮质中减少了20%（p<0.01）。在杏仁核、颞叶皮质或尾状核中，两组之间125I-BH CCK33结合没有差异。
