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老年创伤性脑损伤:使用列线图预测预后的尝试。

Geriatric Traumatic Brain Injury: An Attempt to Predict Outcome Using a Nomogram.

作者信息

Visen Abhyuday, Ramalingam Jinendra K, Sundaram Ponraj K

机构信息

Department of Neurosurgery, Goa Medical College, Bambolim, Goa, India.

出版信息

Neurol India. 2024 Nov 1;72(6):1199-1206. doi: 10.4103/ni.ni_450_22. Epub 2024 Dec 17.

Abstract

BACKGROUND AND OBJECTIVES

With improving life expectancy, the proportion of geriatric patients is steadily increasing in the population and traumatic brain injury (TBI) in the elderly is becoming a problem demanding increasing attention from the health community. We attempted to identify factors that correlate with the outcome (as measured by the Glasgow Outcome Scale [GOS]) in elderly patients with TBI and make a prognostic model.

MATERIALS AND METHODS

A prospective analysis of 220 consecutive TBI patients aged ≥60 years admitted at our hospital was performed. Data about demography, comorbidities, mode of injury, clinico-radiological features, associated injuries, medical/surgical complications, and outcome was analyzed. Patients without imaging findings of TBI and patients with chronic subdural hematoma (SDH) and lesional intracranial hemorrhage were excluded.

RESULTS

The mean age of patients was 69.17 years, with 70.9% being males. Motor vehicle accidents (44%) and ground-level falls (43.7%) were the most common modes of injury. Antiplatelets and anticoagulants were being taken by 14.6% and 1.8% of patients, respectively. Out of 220 patients, 124 patients had mild, 48 had moderate, and 48 had severe head injuries. Median Rotterdam score (RS) was 2. Forty-one patients underwent surgery. The outcome was favorable (GOS 4-5) in 54.1% and unfavorable (GOS 1-3) in 45.9% of patients, with the overall mortality at the end of 1 month being 30.9%. On multivariate regression analysis, Glasgow Coma Scale (GCS), RS, and coagulation abnormality were found to be independent prognostic factors; these three variables were then used to design a nomogram.

CONCLUSION

In the absence of specific geriatric TBI prognostic models, a nomogram using GCS, RS, and coagulation abnormality can be used as a prognostic model.

摘要

背景与目的

随着预期寿命的提高,老年患者在人口中的比例稳步增加,老年人创伤性脑损伤(TBI)正成为一个日益受到卫生界关注的问题。我们试图确定与老年TBI患者的预后(以格拉斯哥预后量表[GOS]衡量)相关的因素,并建立一个预后模型。

材料与方法

对我院收治的220例年龄≥60岁的连续TBI患者进行前瞻性分析。分析了人口统计学、合并症、损伤方式、临床放射学特征、相关损伤、医疗/手术并发症及预后等数据。排除无TBI影像学表现的患者以及慢性硬膜下血肿(SDH)和颅内出血性病变患者。

结果

患者的平均年龄为69.17岁,男性占70.9%。机动车事故(44%)和地面跌倒(43.7%)是最常见的损伤方式。分别有14.6%和1.8%的患者正在服用抗血小板药物和抗凝剂。220例患者中,124例为轻度颅脑损伤,48例为中度颅脑损伤,48例为重度颅脑损伤。鹿特丹评分(RS)中位数为2。41例患者接受了手术。54.1%的患者预后良好(GOS 4 - 5),45.9%的患者预后不良(GOS 1 - 3),1个月时的总死亡率为30.9%。多因素回归分析发现,格拉斯哥昏迷量表(GCS)、RS和凝血异常是独立的预后因素;然后利用这三个变量设计了一个列线图。

结论

在缺乏特定的老年TBI预后模型的情况下,使用GCS、RS和凝血异常的列线图可作为一种预后模型。

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