Sweeney Kerrie, Niblock Aaron, Greenfield Diana, Snowden John
Department of Haematology Northern Health and Social Care Trust Antrim Area Hospital Antrim UK.
Department of Haematology Ulster University School of Medicine Londonderry UK.
EJHaem. 2024 Nov 15;5(6):1359-1362. doi: 10.1002/jha2.999. eCollection 2024 Dec.
Advances in myeloma have resulted in improved prognosis for patients. However complications of the disease and treatment, pose a risk of specific long-term consequences. An audit tool was adapted to assess adherence to the British Society for Haematology guidelines for screening and management of long-term myeloma consequences. Thereafter a screening checklist was developed to prompt the implementation of guideline recommendations, followed by a re-audit evaluating the effectiveness of the checklist. Good baseline practice was identified relating to vaccinations, herpes prophylaxis, dental assessment, bisphosphonates, calcium/ vitamin D supplementation and holistic needs assessments. However gaps in practice included monitoring of lipids, HBA1C, NT-pro-BNP/ BNP, BMI, calcium/ vitamin D and parathyroid hormone in kidney disease, endocrine screening and geriatric assessments. Re-audit demonstrated that geriatric assessment remains a gap in practice, however other standards now scored between 80 to 100% compliance, highlighting the benefits of a screening checklist, to increase adherence to recommendations.
骨髓瘤研究的进展使患者的预后得到改善。然而,该疾病及其治疗的并发症会带来特定长期后果的风险。采用了一种审核工具来评估对英国血液学学会关于骨髓瘤长期后果筛查和管理指南的遵循情况。此后制定了一份筛查清单,以促使指南建议的实施,随后进行了一次重新审核,评估该清单的有效性。确定了在疫苗接种、疱疹预防、牙科评估、双膦酸盐、钙/维生素D补充以及整体需求评估方面的良好基线做法。然而,实践中的差距包括对脂质、糖化血红蛋白、N末端脑钠肽前体/脑钠肽、体重指数、钙/维生素D以及肾病中的甲状旁腺激素的监测、内分泌筛查和老年评估。重新审核表明,老年评估在实践中仍然存在差距,但其他标准现在的合规率在80%至100%之间,突出了筛查清单在提高对建议的遵循方面的益处。