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PCSK7 levels in women with and without PCOS.患有和未患有多囊卵巢综合征的女性体内的前蛋白转化酶枯草溶菌素/kexin 7型(PCSK7)水平。
J Clin Transl Endocrinol. 2024 Nov 28;38:100376. doi: 10.1016/j.jcte.2024.100376. eCollection 2024 Dec.
2
PCSK7, a potential target for the treatment of age-related macular degeneration: inhibition of retinal epithelial cell death.前蛋白转化酶枯草溶菌素7(PCSK7),一种治疗年龄相关性黄斑变性的潜在靶点:抑制视网膜上皮细胞死亡。
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Post-Transcriptional Effects of miRNAs on PCSK7 Expression and Function: miR-125a-5p, miR-143-3p, and miR-409-3p as Negative Regulators.微小RNA对前蛋白转化酶枯草溶菌素9(PCSK7)表达和功能的转录后效应:miR-125a-5p、miR-143-3p和miR-409-3p作为负调控因子
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PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.前蛋白转化酶枯草溶菌素/kexin 9型(PCSK7):载脂蛋白B的新型调节因子及抗非酒精性脂肪性肝病的潜在靶点。
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The Biology and Clinical Implications of PCSK7.前蛋白转化酶枯草溶菌素7的生物学特性及临床意义
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gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients.基因变异将动脉粥样硬化性血脂异常与非酒精性脂肪性肝病患者的肝炎症联系起来。
J Lipid Res. 2019 Jun;60(6):1144-1153. doi: 10.1194/jlr.P090449. Epub 2019 Mar 27.
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Proprotein convertase subtilisin/kexin type 7 (PCSK7) is essential for the zebrafish development and bioavailability of transforming growth factor β1a (TGFβ1a).脯氨酸内切酶枯草溶菌素/柯萨奇蛋白酶 7(PCSK7)是斑马鱼发育和转化生长因子β1a(TGFβ1a)生物利用度所必需的。
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Novel association to the proprotein convertase PCSK7 gene locus revealed by analysing soluble transferrin receptor (sTfR) levels.通过分析可溶性转铁蛋白受体 (sTfR) 水平,发现了与前蛋白转化酶枯草溶菌素 7 (PCSK7) 基因座的新关联。
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10
PCSK7 genotype modifies effect of a weight-loss diet on 2-year changes of insulin resistance: the POUNDS LOST trial.前蛋白转化酶枯草溶菌素/kexin 9型(PCSK7)基因分型可改变减肥饮食对胰岛素抵抗2年变化的影响:减重试验
Diabetes Care. 2015 Mar;38(3):439-44. doi: 10.2337/dc14-0473. Epub 2014 Dec 12.

本文引用的文献

1
PCSK7: A novel regulator of apolipoprotein B and a potential target against non-alcoholic fatty liver disease.前蛋白转化酶枯草溶菌素/kexin 9型(PCSK7):载脂蛋白B的新型调节因子及抗非酒精性脂肪性肝病的潜在靶点。
Metabolism. 2024 Jan;150:155736. doi: 10.1016/j.metabol.2023.155736. Epub 2023 Nov 13.
2
Polycystic Ovary Syndrome: Etiology, Current Management, and Future Therapeutics.多囊卵巢综合征:病因、当前治疗及未来疗法
J Clin Med. 2023 Feb 11;12(4):1454. doi: 10.3390/jcm12041454.
3
Systemic and ovarian inflammation in women with polycystic ovary syndrome.多囊卵巢综合征女性的全身和卵巢炎症。
J Reprod Immunol. 2022 Jun;151:103628. doi: 10.1016/j.jri.2022.103628. Epub 2022 Apr 16.
4
Effect of induced hypoglycemia on inflammation and oxidative stress in type 2 diabetes and control subjects.诱导性低血糖对 2 型糖尿病患者及对照者炎症和氧化应激的影响。
Sci Rep. 2020 Mar 16;10(1):4750. doi: 10.1038/s41598-020-61531-z.
5
Dyslipidemia involvement in the development of polycystic ovary syndrome.脂代谢紊乱与多囊卵巢综合征的发生发展。
Taiwan J Obstet Gynecol. 2019 Jul;58(4):447-453. doi: 10.1016/j.tjog.2019.05.003.
6
gene variation bridges atherogenic dyslipidemia with hepatic inflammation in NAFLD patients.基因变异将动脉粥样硬化性血脂异常与非酒精性脂肪性肝病患者的肝炎症联系起来。
J Lipid Res. 2019 Jun;60(6):1144-1153. doi: 10.1194/jlr.P090449. Epub 2019 Mar 27.
7
Anti-Müllerian hormone measurement for the diagnosis of polycystic ovary syndrome.抗缪勒管激素测定用于多囊卵巢综合征的诊断。
Clin Endocrinol (Oxf). 2018 Feb;88(2):258-262. doi: 10.1111/cen.13517. Epub 2017 Dec 7.
8
PCSK7 genotype modifies effect of a weight-loss diet on 2-year changes of insulin resistance: the POUNDS LOST trial.前蛋白转化酶枯草溶菌素/kexin 9型(PCSK7)基因分型可改变减肥饮食对胰岛素抵抗2年变化的影响:减重试验
Diabetes Care. 2015 Mar;38(3):439-44. doi: 10.2337/dc14-0473. Epub 2014 Dec 12.
9
Proprotein convertases in health and disease.健康与疾病中的前蛋白转化酶。
N Engl J Med. 2011 Dec 29;365(26):2507-18. doi: 10.1056/NEJMra1106700.
10
Hormonal regulation of proprotein convertase subtilisin/kexin type 5 expression during ovarian follicle development in the rat.大鼠卵巢卵泡发育过程中前蛋白转化酶枯草杆菌蛋白酶/kexin 5型表达的激素调节
Mol Cell Endocrinol. 2008 Jul 16;289(1-2):29-37. doi: 10.1016/j.mce.2008.04.006. Epub 2008 Apr 22.

PCSK7 levels in women with and without PCOS.

作者信息

Atkin Stephen L, Butler Alexandra E, Jamialahmadi Tannaz, Sahebkar Amirhossein

机构信息

Royal College of Surgeons in Ireland, PO Box 15503, Adliya, Bahrain.

Pharmaceutical Research Center, Pharmaceutical Technology Institute, Mashhad University of Medical Sciences, Mashhad, Iran.

出版信息

J Clin Transl Endocrinol. 2024 Nov 28;38:100376. doi: 10.1016/j.jcte.2024.100376. eCollection 2024 Dec.

DOI:10.1016/j.jcte.2024.100376
PMID:39691660
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11650127/
Abstract
摘要