Arai Kiyotaka, Nakamura Shinichi, Matsubara Kanami, Ozaki Yuma, Kadekaru Sho, Sugiyama Akihiko, Mitsui Ikki, Akashi Natsuki, Yoshitake Ryohei, Kutara Kenji
Laboratory of Veterinary Surgery, Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Ehime, Japan.
Laboratory of Veterinary Pathology, Faculty of Veterinary Medicine, Okayama University of Science, Imabari, Ehime, Japan.
JFMS Open Rep. 2024 Dec 16;10(2):20551169241291842. doi: 10.1177/20551169241291842. eCollection 2024 Jul-Dec.
A 13-year-old castrated male American Shorthair cat was referred for evaluation following a 3-week history of poor balance and decreased activity. The MRI findings revealed a well-defined left caudal cerebellar mass with a diameter of 1.2 cm, consistent with a meningioma. CT and MRI scans did not reveal metastasis. After a suboccipital craniotomy, the mass was resected subtotally as a result of parenchymal invasion. A histopathological examination revealed a benign fibrous meningioma with invasion into the cerebellum at the tumour margins. Postoperatively, the cat remained asymptomatic for 25 months, but ataxia recurred, and tumour recurrence was confirmed using MRI and post-mortem examination.
This case demonstrates that even feline meningiomas with benign features can exhibit brain invasion. Since brain invasion is an indicator of malignancy in meningioma, a detailed histopathological evaluation of the tumour margins is essential for accurate grading and prognosis.
一只13岁去势的雄性美国短毛猫，在出现3周的平衡能力差和活动减少的病史后被转诊进行评估。磁共振成像（MRI）结果显示左小脑尾侧有一个边界清晰的肿块，直径为1.2厘米，符合脑膜瘤表现。计算机断层扫描（CT）和MRI扫描未发现转移。在进行枕下开颅手术后，由于实质侵犯，肿块被次全切除。组织病理学检查显示为良性纤维性脑膜瘤，肿瘤边缘侵犯小脑。术后，这只猫在25个月内无症状，但共济失调复发，通过MRI和尸检证实肿瘤复发。
本病例表明，即使是具有良性特征的猫脑膜瘤也可表现出脑侵犯。由于脑侵犯是脑膜瘤恶性程度的一个指标，对肿瘤边缘进行详细的组织病理学评估对于准确分级和预后至关重要。
