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重症监护中的气管导管感染:对重症监护病房环境中影响因素、微生物病原体及缓解策略的叙述性综述

Tracheal tube infections in critical care: A narrative review of influencing factors, microbial agents, and mitigation strategies in intensive care unit settings.

作者信息

Motallebirad Tahereh, Mohammadi Mohammad Reza, Jadidi Ali, Safarabadi Mehdi, Kerami Azam, Azadi Davood, Hussein Ehab Salam

机构信息

Department of Research and Development, Satras Biotechnology Company, Khomein Branch, Islamic Azad University, Khomein, Iran.

Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran.

出版信息

SAGE Open Med. 2024 Dec 16;12:20503121241306951. doi: 10.1177/20503121241306951. eCollection 2024.

Abstract

Tracheal tube infections pose significant challenges in the management of mechanically ventilated patients in intensive care units. These infections contribute to prolonged intensive care unit stays, increased healthcare costs, the spread of antibiotic resistance, and poor patient outcomes. This study aims to elucidate the complex relationship between environmental factors, hospital practices, and the incidence of tracheal tube infections. Our comprehensive review explores the impact of factors such as air quality, water sources, equipment contamination, ventilation strategies, infection control protocols, and microbial reservoirs within hospital settings on tracheal tube infection rates. Additionally, it investigates global variations in tracheal tube infection prevalence, which are influenced by differences in healthcare infrastructure, infection control adherence, antibiotic resistance profiles, and patient demographics. Our findings highlight the importance of targeted interventions and collaborative approaches to reduce the burden of tracheal tube infections and improve patient care in intensive care units. By fully understanding the interplay between environmental conditions and hospital practices, effective prevention and management strategies can be developed to reduce the impact of tracheal tube infections on patient outcomes and healthcare resources, ultimately enhancing the quality of care in critical care settings.

摘要

气管导管感染给重症监护病房中接受机械通气的患者的管理带来了重大挑战。这些感染会导致重症监护病房住院时间延长、医疗成本增加、抗生素耐药性传播以及患者预后不良。本研究旨在阐明环境因素、医院做法与气管导管感染发生率之间的复杂关系。我们的综合综述探讨了空气质量、水源、设备污染、通气策略、感染控制方案以及医院环境中的微生物储存库等因素对气管导管感染率的影响。此外,它还调查了气管导管感染患病率的全球差异,这些差异受到医疗基础设施、感染控制依从性、抗生素耐药性概况以及患者人口统计学差异的影响。我们的研究结果强调了针对性干预措施和协作方法对于减轻气管导管感染负担以及改善重症监护病房患者护理的重要性。通过充分了解环境条件与医院做法之间的相互作用,可以制定有效的预防和管理策略,以减少气管导管感染对患者预后和医疗资源的影响,最终提高重症监护环境中的护理质量。

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