Leonard Stephanie A, Xu Xiao, Davies-Balch Shantay, Main Elliott K, Bateman Brian T, Rehkopf David H, Lee Henry C, Illuzzi Jessica, Igbinosa Irogue, Iwekaogwu Ijeoma, Lyell Deirdre J
Department of Obstetrics and Gynecology, Stanford School of Medicine, Stanford, California.
Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut.
Am J Epidemiol. 2024 Dec 16. doi: 10.1093/aje/kwae459.
Persistent racial and ethnic disparities exist in severe maternal and neonatal morbidity, which may be due in part to differences in labor and delivery unit practices across hospitals. We used data collected from 184 hospitals in California (2015-2018) to assess whether nulliparous individuals with low-risk pregnancies differ by race and ethnicity in giving birth at hospitals that tend to use lower-interventional labor and delivery unit practices, and whether such differences contribute to disparities in severe maternal and neonatal morbidity. We classified labor and delivery units as higher- or lower-interventional based on a latent class analysis of survey responses about the frequency of using lower-interventional practices. We used a modified doubly robust g-estimator to estimate counterfactual disparity measures, setting all hospitals to be lower-interventional. Among 348,990 low-risk livebirths, the proportion occurring at lower-interventional hospitals was lowest in Black and Latino individuals (17% and 16%, respectively) and highest in American Indian and Alaska Native (AI/AN) and White individuals (29% in both). Severe maternal and neonatal morbidity occurred most frequently among AI/AN individuals. Counterfactual disparity measures suggested that if all births occurred at lower-interventional hospitals, racial and ethnic disparities in the outcomes would modestly increase, except for severe neonatal morbidity among AI/AN individuals.
严重孕产妇和新生儿发病率方面持续存在种族和族裔差异,这可能部分归因于各医院在 labor 和分娩单元的做法存在差异。我们使用从加利福尼亚州184家医院收集的数据(2015 - 2018年)来评估低风险妊娠的初产妇在倾向于采用低干预 labor 和分娩单元做法的医院分娩时,是否因种族和族裔而有所不同,以及这些差异是否导致严重孕产妇和新生儿发病率的差异。我们根据对关于使用低干预做法频率的调查回复进行潜在类别分析,将 labor 和分娩单元分类为高干预或低干预。我们使用改进的双重稳健g估计器来估计反事实差异度量,将所有医院设定为低干预。在348,990例低风险活产中,在低干预医院分娩的比例在黑人和拉丁裔个体中最低(分别为17%和16%),在美国印第安人和阿拉斯加原住民(AI/AN)以及白人个体中最高(两者均为29%)。严重孕产妇和新生儿发病率在AI/AN个体中最为常见。反事实差异度量表明,如果所有分娩都在低干预医院进行,除了AI/AN个体中的严重新生儿发病率外,结果中的种族和族裔差异将略有增加。