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小儿髋关节手术中囊周神经组(PENG)阻滞与腰竖脊肌平面阻滞(ESPB)的比较:一项随机、双盲、对照试验

Pericapsular Nerve Group (PENG) Block Versus Lumbar Erector Spinae Plane Block (ESPB) in Pediatric Hip Surgery: A Randomized, Double-Blinded, Controlled Trial.

作者信息

Reysner Malgorzata, Reysner Tomasz, Janusz Piotr, Kowalski Grzegorz, Shadi Milud, Daroszewski Przemysław, Wieczorowska-Tobis Katarzyna, Kotwicki Tomasz

机构信息

Departments of Palliative Medicine.

Spine Disorders and Pediatric Orthopedics, University of Medical Sciences.

出版信息

J Pediatr Orthop. 2025 Apr 1;45(4):e324-e330. doi: 10.1097/BPO.0000000000002882. Epub 2024 Dec 18.

Abstract

BACKGROUND

The effectiveness and safety of the pericapsular nerve group (PENG) block and lumbar erector spinae plane block (ESPB) in pediatric hip surgeries is limited mainly to case reports. This study assessed the efficacy of ultrasound-guided PENG block versus lumbar ESPB under spinal anesthesia.

METHODS

Ninety patients aged 2 to 7 years, ASA I-III scheduled for hip surgery were randomly assigned to 3 equal groups, each receiving the PENG block group (n=30), the ESPB group (n=30), or the control group (n=30). After the spinal anesthesia, the block was performed with 0.5 kg/mL of 0.2% ropivacaine. The primary outcome was the pain scores (FLACC) 48 hours after surgery. The secondary outcomes included postoperative FLACC pain scores, neutrophile-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and total opioid consumption.

RESULTS

The FLACC score was significantly lower in the lumbar ESPB and PENG groups compared with the control group ( P <0.0001) at all time points. The NLR and PLR levels were substantially lower in the PENG and lumbar ESPB groups ( P <0.0001) compared with the control group. The NLR and PLR levels were significantly lower in the PENG and lumbar ESPB groups compared with the control group ( P <0.0001). The total opioid consumption was significantly lower in the PENG and lumbar ESPB groups compared with the control group ( P <0.0001). Forty-three percent of children in the PENG group and 50% of children in the lumbar ESPB group did not require opioids postoperatively.

CONCLUSIONS

The PENG block and the lumbar ESPB provide efficient postoperative analgesia in children undergoing hip surgery. The PENG block and lumbar ESPB lower cumulative opioid consumption and the stress response to surgery, expressed by NLR and PLR levels.

LEVEL OF EVIDENCE

Level I.

摘要

背景

小儿髋关节手术中关节周围神经群(PENG)阻滞和腰段竖脊肌平面阻滞(ESPB)的有效性和安全性主要限于病例报告。本研究评估了超声引导下PENG阻滞与腰段ESPB在脊髓麻醉下的疗效。

方法

90例年龄2至7岁、ASA I-III级计划行髋关节手术的患者被随机分为3组,每组30例,分别接受PENG阻滞组(n=30)、ESPB组(n=30)或对照组(n=30)。脊髓麻醉后,用0.2%罗哌卡因0.5 kg/mL进行阻滞。主要结局是术后48小时的疼痛评分(面部、腿部、活动、哭闹、安慰评分法[FLACC])。次要结局包括术后FLACC疼痛评分、中性粒细胞与淋巴细胞比值(NLR)、血小板与淋巴细胞比值(PLR)以及阿片类药物总消耗量。

结果

在所有时间点,腰段ESPB组和PENG组的FLACC评分均显著低于对照组(P<0.0001)。与对照组相比,PENG组和腰段ESPB组的NLR和PLR水平显著降低(P<0.0001)。与对照组相比,PENG组和腰段ESPB组的NLR和PLR水平显著降低(P<0.0001)。与对照组相比,PENG组和腰段ESPB组的阿片类药物总消耗量显著降低(P<0.0001)。PENG组43%的儿童和腰段ESPB组50%的儿童术后不需要使用阿片类药物。

结论

PENG阻滞和腰段ESPB为接受髋关节手术的儿童提供了有效的术后镇痛。PENG阻滞和腰段ESPB降低了阿片类药物的累积消耗量以及由NLR和PLR水平所表示的对手术的应激反应。

证据水平

I级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee3c/11875410/2b489f3d8a9a/bpo-45-e324-g001.jpg

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