Samson W K, McDonald J K, Lumpkin M D
Neuroendocrinology. 1985 Jan;40(1):68-71. doi: 10.1159/000124053.
Immobilization of adult male rats resulted in concomitant, significant releases of prolactin (PRL) and oxytocin (OT). Naloxone (0.2 mg/kg, i.p.) administration 30 min prior to initiation of restraint resulted in a significant diminution of the PRL response to stress. On the other hand, a significant augmentation of OT release was observed. These results demonstrate that concomitant releases of OT and PRL in response to a given physiologic stimulus (stress) can be dissociated and suggest that the hypothalamic events which are responsible for the release of these hormones during stress are different.
成年雄性大鼠被固定后，催乳素（PRL）和催产素（OT）同时大量释放。在开始固定前30分钟腹腔注射纳洛酮（0.2毫克/千克），可显著减弱应激引起的PRL反应。另一方面，观察到OT释放显著增加。这些结果表明，对给定生理刺激（应激）的OT和PRL同时释放可以分离，这表明在应激期间负责这些激素释放的下丘脑事件是不同的。
