Delwaide P J, Schoenen J, De Pasqua V
Neurology. 1985 Feb;35(2):174-9. doi: 10.1212/wnl.35.2.174.
Lumbosacral spinal evoked potentials were recorded percutaneously in 22 MS patients with spinal symptoms and in 24 age-matched normal volunteers. Latencies, durations, and areas of waves R and A (level S1) as well as S and P2 (level Th12) were analyzed. The most significant result observed in the MS group was a reduction of the ratio between the areas of P2 and S. The reduction was strongly correlated with intensity of spasticity, but not with other clinical features. The P2/S ratio can thus be proposed as an electrophysiologic measure of spasticity.
对22例有脊髓症状的多发性硬化症（MS）患者及24名年龄匹配的正常志愿者经皮记录腰骶部脊髓诱发电位。分析了R波和A波（S1水平）以及S波和P2波（T12水平）的潜伏期、持续时间和波幅面积。在MS组中观察到的最显著结果是P2波和S波波幅面积之比降低。该降低与痉挛强度密切相关，但与其他临床特征无关。因此，P2/S比值可作为痉挛的一种电生理指标。
