Karamazı Yasin, Emre Mustafa, Uçar Sümeyye, Aksoy Gülsevinç, Emre Toygar, Tokuş Murat
Faculty of Medicine, Department of Biophysics, Çukurova University, Adana, Türkiye.
Faculty of Medicine, Department of Anatomy, Erciyes University, Kayseri, Türkiye.
Electromagn Biol Med. 2025 Jan 2;44(1):17-25. doi: 10.1080/15368378.2024.2438608. Epub 2024 Dec 18.
This study examined the impact of 6 GHz (0.054 W/kg SAR) Radiofrequency-Electromagnetic Field (RF-EMF) on prenatal bone development. In this study, 20 female and 20 male Wistar Albino rats divided into four groups. The Control group received no treatment, while in Group-I, only male rats were exposed to RF-EMF, female rats had no exposure. Group-II, both male and female rats received RF-EMF treatment. While in Group-III, only female rats were exposed to RF-EMF, male rats had no exposure. The exposure lasted 4 hours per day for 6 weeks. The rats were then allowed to mate within the group. After pregnancy, pregnant rats (Group-II and III) were exposed 4 hours per day for 18 days. On the 18th day of gestation, fetuses were removed and their weight and various lengths were measured. The skeletal system development of fetuses was examined with double skeletal staining method and assessed ossification in the extremities. In the study, fetal weights, head-tail length, occipital-frontal and parietal-parietal lengths significantly increased in all exposure groups when compared to the control group ( < 0.001). Although occipital-frontal length was smallest in Group-I, Group-II and Group-III were more higher than the control group ( < 0.001). The bones of the anterior and posterior extremities showed significant increases in length, ossification zone length, and ossification percentage in all experimental groups compared to the control group ( < 0.001). Our study showed that rats exposed to 6 GHz (0.054 W/kg) RF-EMF during the prenatal period had significant increases in bone development.
本研究考察了6吉赫兹(比吸收率为0.054瓦/千克)射频电磁场(RF - EMF)对产前骨骼发育的影响。在本研究中,将20只雌性和20只雄性Wistar白化大鼠分为四组。对照组不接受任何处理,而在第一组中,仅雄性大鼠暴露于RF - EMF,雌性大鼠未暴露。第二组中,雄性和雌性大鼠均接受RF - EMF处理。而在第三组中,仅雌性大鼠暴露于RF - EMF,雄性大鼠未暴露。暴露持续6周,每天4小时。然后让大鼠在组内交配。怀孕后,怀孕大鼠(第二组和第三组)每天暴露4小时,持续18天。在妊娠第18天,取出胎儿并测量其体重和各种长度。采用双重骨骼染色法检查胎儿的骨骼系统发育,并评估四肢的骨化情况。在该研究中,与对照组相比,所有暴露组的胎儿体重、头尾长度、枕额长度和顶顶长度均显著增加(<0.001)。虽然第一组的枕额长度最小,但第二组和第三组均高于对照组(<0.001)。与对照组相比,所有实验组的前后肢骨骼在长度、骨化区长度和骨化百分比方面均显著增加(<0.001)。我们的研究表明,产前暴露于6吉赫兹(0.054瓦/千克)RF - EMF的大鼠骨骼发育显著增加。