Huhtanen Mia, Mikola Katriina, Kiukkonen Anu, Palotie Tuula
Orthodontics, Department of Oral and Maxillofacial Diseases, Clinicum, Faculty of Medicine, University of Helsinki, Helsinki, Finland; Department of Oral and Maxillofacial Diseases, Helsinki University Hospital, Helsinki, Finland; Oral Health Care, Espoo Health Care Centre, Western Uusimaa Wellbeing Services County, Espoo, Finland.
New Children's Hospital, Paediatric Research Centre University of Helsinki and Helsinki University Hospital, Helsinki, Finland.
Acta Odontol Scand. 2024 Dec 18;83:682-689. doi: 10.2340/aos.v83.42438.
Temporomandibular joint (TMJ) arthritis is a common finding in juvenile idiopathic arthritis (JIA) patients. TMJ arthritis can cause significant disturbances in TMJ function and growth without treatment. Our aim was to evaluate the effectiveness of medical treatments used to manage TMJ arthritis and how to evaluate the outcome of the treatment. Furthermore, this study aimed to ascertain the prevalence of TMJ arthritis in JIA patients and investigate the potential impact of specific factors.
Between 2015 and 2019, a total of 194 JIA patients who received treatment at the Department of Oral and Maxillofacial Diseases, Helsinki University Hospital, Finland were included in the study. We retrospectively screened the patient records and imaging studies to find out how many patients had TMJ arthritis and what medication was used to treat it.
Maximal incisal mouth opening (MIO) increased significantly with patients whose TMJ arthritis was successfully treated with intra-articular corticosteroid injection (IACI). Almost all patients with TMJ arthritis were treated with an IACI at some point during their treatment. Overall, 99 patients (51%) had been diagnosed with TMJ arthritis. No statistical difference was found between the prevalence of TMJ arthritis and different JIA subtypes, JIA onset time, gender, or immunological factors.
MIO is an easy way to evaluate the treatment outcome and possible disease activation of TMJ arthritis. The prevalence of TMJ arthritis is high among JIA patients. In our study, we could not find any parameters that predict TMJ arthritis, and despite systemic medication, TMJ arthritis might occur.
颞下颌关节（TMJ）关节炎在幼年特发性关节炎（JIA）患者中很常见。未经治疗的TMJ关节炎可导致TMJ功能和生长出现严重紊乱。我们的目的是评估用于治疗TMJ关节炎的药物治疗效果以及如何评估治疗结果。此外，本研究旨在确定JIA患者中TMJ关节炎的患病率，并调查特定因素的潜在影响。
2015年至2019年期间，芬兰赫尔辛基大学医院口腔颌面疾病科共纳入194例接受治疗的JIA患者。我们回顾性筛查了患者记录和影像学研究，以确定有多少患者患有TMJ关节炎以及使用了何种药物进行治疗。
关节内注射皮质类固醇（IACI）成功治疗TMJ关节炎的患者，其最大切牙开口度（MIO）显著增加。几乎所有TMJ关节炎患者在治疗过程中的某个阶段都接受了IACI治疗。总体而言，99例患者（51%）被诊断患有TMJ关节炎。TMJ关节炎的患病率与不同的JIA亚型、JIA发病时间、性别或免疫因素之间未发现统计学差异。
MIO是评估TMJ关节炎治疗结果和可能的疾病活动的简便方法。JIA患者中TMJ关节炎的患病率很高。在我们的研究中，我们未发现任何可预测TMJ关节炎的参数，并且尽管进行了全身用药，TMJ关节炎仍可能发生。
