Burkhart Jennaye G, Smith Ross P, Hill Terra M, Winfield Robert D
Department of Surgery, University of Kansas Medical Center, Kansas City, KS, USA.
University of Kansas School of Medicine, Wichita, KS, USA.
Am Surg. 2025 Apr;91(4):626-632. doi: 10.1177/00031348241309563. Epub 2024 Dec 18.
Viscoelastic hemostatic assays (VHAs) have become a valuable tool in guiding transfusion therapy, particularly in trauma care. While various forms of VHA exist, all provide a quantitative assessment of clot kinetics, strength, and dissolution. Studies have demonstrated that VHA can reduce both mortality and utilization of blood products in the general population. Interpreting VHA results requires consideration of specific patient factors, such as age and altered physiological properties as in pregnancy and the process of aging. Further research is needed to establish accurate reference ranges for these specific populations. This review article provides a comprehensive overview of the technical aspects of VHA as well as their clinical uses in trauma resuscitation.
粘弹性止血检测（VHA）已成为指导输血治疗的一项重要工具，尤其是在创伤护理中。虽然存在多种形式的VHA，但它们都能对凝血动力学、强度和溶解进行定量评估。研究表明，VHA可降低普通人群的死亡率和血液制品的使用量。解读VHA结果需要考虑特定的患者因素，如年龄以及妊娠和衰老过程中生理特性的改变。需要进一步研究来为这些特定人群建立准确的参考范围。本文综述全面概述了VHA的技术方面及其在创伤复苏中的临床应用。
