Health Technol Assess. 2018 Jul;22(39):1-176. doi: 10.3310/hta22390.
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Rheumatoid arthritis secondary non-responders to TNF can attain an efficacious and safe response by switching to certolizumab pegol: a phase IV, randomised, multicentre, double-blind, 12-week study, followed by a 12-week open-label phase.
类风湿关节炎继发 TNF 治疗应答不佳的患者转换使用培塞利珠单抗后可获得有效且安全的应答:一项 IV 期、随机、多中心、双盲、为期 12 周的研究,随后是为期 12 周的开放标签期。
Ann Rheum Dis. 2014 Dec;73(12):2174-7. doi: 10.1136/annrheumdis-2014-205325. Epub 2014 Jun 27.