Brown J J, vanSonnenberg E, Gerber K H, Strich G, Wittich G R, Slutsky R A
Radiology. 1985 Mar;154(3):727-31. doi: 10.1148/radiology.154.3.3969478.
Seventy-three fluid samples obtained via percutaneous aspiration and drainage were analyzed by proton magnetic resonance spectroscopy. The fluids included abscess contents, bile, ascitic fluid, cyst and pseudocyst fluid, urine, hematomas, pleural fluid, lymphoceles, seromas, cerebrospinal fluid, pancreatic ductal fluid, and necrotic tumor. They were grouped by their clinical etiology and analyzed with respect to their inherent magnetic relaxation properties. In addition, some of the samples were tested for the following chemical parameters which were correlated with T1 and T2 values: total protein content (n = 36), osmolality (n = 24), specific gravity (n = 11), and amylase levels (n = 23). A large overlap was found in the T1 (spin-lattice) and T2 (spin-spin) relaxation times of the fluids; however, the mean T1 values of abscesses and hematomas were significantly lower than those of other fluids. Similar variability was seen in T2 values, though hematomas and abscesses again could be distinguished by shorter relaxation times. The spin-lattice (1/T1) and spin-spin relaxation rates (1/T2) showed a moderate correlation with total protein content, osmolality, and specific gravity. It is concluded that there is some predictability to MR analysis of body fluids, though the overlap in magnetic relaxation times limits specificity.
通过经皮穿刺抽吸和引流获得的73份液体样本，采用质子磁共振波谱进行分析。这些液体包括脓肿内容物、胆汁、腹水、囊肿和假性囊肿液、尿液、血肿、胸腔积液、淋巴囊肿、血清肿、脑脊液、胰管液和坏死肿瘤。根据临床病因对它们进行分组，并就其固有的磁弛豫特性进行分析。此外，对部分样本进行了以下与T1和T2值相关的化学参数检测：总蛋白含量（n = 36）、渗透压（n = 24）、比重（n = 11）和淀粉酶水平（n = 23）。发现这些液体的T1（自旋-晶格）和T2（自旋-自旋）弛豫时间有很大重叠；然而，脓肿和血肿的平均T1值显著低于其他液体。T2值也有类似的变异性，不过血肿和脓肿再次可通过较短的弛豫时间区分开来。自旋-晶格（1/T1）和自旋-自旋弛豫率（1/T2）与总蛋白含量、渗透压和比重呈中度相关。得出的结论是，尽管磁弛豫时间的重叠限制了特异性，但对体液的磁共振分析仍具有一定的可预测性。
