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Steps forward in the treatment of IgA nephropathy.

作者信息

Coppo Rosanna

机构信息

Fondazione Ricerca Molinette, Turin, Italy.

出版信息

Nat Rev Nephrol. 2025 Apr;21(4):218-219. doi: 10.1038/s41581-024-00925-y.

DOI:10.1038/s41581-024-00925-y
PMID:39695336
Abstract
摘要

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J Am Soc Nephrol. 2025 Feb 1;36(2):324. doi: 10.1681/ASN.0000000553. Epub 2024 Nov 15.
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Semaglutide for Chronic Kidney Disease in Type 2 Diabetes. Reply.司美格鲁肽用于2型糖尿病合并慢性肾脏病。回复。
N Engl J Med. 2024 Nov 7;391(18):1757. doi: 10.1056/NEJMc2410532.
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The Selective Endothelin Receptor Antagonist SC0062 in IgA Nephropathy: A Randomized Double-Blind Placebo-Controlled Clinical Trial.
选择性内皮素受体拮抗剂SC0062治疗IgA肾病:一项随机双盲安慰剂对照临床试验
J Am Soc Nephrol. 2025 Apr 1;36(4):657-667. doi: 10.1681/ASN.0000000538. Epub 2024 Oct 26.
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Long-Term Results from an Open-Label Extension Study of Atacicept for the Treatment of IgA Nephropathy.阿他西普治疗IgA肾病开放标签扩展研究的长期结果
J Am Soc Nephrol. 2025 Apr 1;36(4):679-687. doi: 10.1681/ASN.0000000541. Epub 2024 Oct 26.
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Atrasentan in Patients with IgA Nephropathy.阿曲生坦用于治疗IgA肾病患者。
N Engl J Med. 2025 Feb 6;392(6):544-554. doi: 10.1056/NEJMoa2409415. Epub 2024 Oct 25.
6
A phase 2b, randomized, double-blind, placebo-controlled, clinical trial of atacicept for treatment of IgA nephropathy.一项评估阿他西普治疗IgA肾病的2b期随机双盲安慰剂对照临床试验。
Kidney Int. 2024 Jun;105(6):1306-1315. doi: 10.1016/j.kint.2024.03.012. Epub 2024 Mar 27.
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A Phase 2 Trial of Sibeprenlimab in Patients with IgA Nephropathy.Sibeprenlimab 治疗 IgA 肾病患者的 II 期临床试验。
N Engl J Med. 2024 Jan 4;390(1):20-31. doi: 10.1056/NEJMoa2305635. Epub 2023 Nov 2.
8
Executive summary of the KDIGO 2021 Guideline for the Management of Glomerular Diseases.KDIGO 2021肾小球疾病管理指南执行摘要。
Kidney Int. 2021 Oct;100(4):753-779. doi: 10.1016/j.kint.2021.05.015.
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Association of Treatment Effects on Early Change in Urine Protein and Treatment Effects on GFR Slope in IgA Nephropathy: An Individual Participant Meta-analysis.IgA 肾病中早期尿蛋白变化的治疗效果与 GFR 斜率的治疗效果关联:一项个体参与者荟萃分析。
Am J Kidney Dis. 2021 Sep;78(3):340-349.e1. doi: 10.1053/j.ajkd.2021.03.007. Epub 2021 Mar 26.
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IgA Nephropathy: An Interesting Autoimmune Kidney Disease.IgA 肾病:一种有趣的自身免疫性肾脏疾病。
Am J Med Sci. 2021 Feb;361(2):176-194. doi: 10.1016/j.amjms.2020.10.003. Epub 2020 Oct 8.