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单侧双通道内镜下腰椎椎间融合术中隐匿性失血的危险因素:一项单中心回顾性研究

Risk factors for hidden blood loss in unilateral biportal endoscopic lumbar interbody fusion : a single-center retrospective study.

作者信息

Jin Jian-Fang, Chen Hao-Ran, Peng Yu-Jian, Dai Jun, Wang Qian-Liang, Yan Jun

机构信息

Department of Hospital Outpatient, The Second Affiliated Hospital of Soochow University, Suzhou, Jiangsu, 215004, China.

Department of Orthopedic Surgery, The Second Affiliated Hospital of Soochow University, No.1055 Sanxiang Road, Gusu District, Suzhou, Jiangsu, 215004, China.

出版信息

BMC Musculoskelet Disord. 2024 Dec 18;25(1):1017. doi: 10.1186/s12891-024-08104-7.

DOI:10.1186/s12891-024-08104-7
PMID:39695594
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11657688/
Abstract

BACKGROUND

Hidden blood loss (HBL) is often ignored unilateral biportal endoscopic interbody fusion surgery (ULIF). We investigated the amount and influencing factors of HBL in ULIF surgery in this study.

METHODS

From October 2020 to November 2023, 100 patients' clinical and radiological data were retrospectively analyzed. Pearson or Spearman correlation and multivariate linear regression were used to identify factors linked to HBL.

RESULTS

The mean hidden blood loss (HBL) was 255.84 ± 290.89 ml, making up 62.48% of total blood loss. Correlation analysis showed HBL positively related to ASA classification (P = 0.009), operation time (P = 0.004), number of operation levels (P = 0.046), and paraspinal muscle thickness (P = 0.043), but negatively related to tranexamic acid use (P = 0.001). A multivariate linear regression analysis showed that HBL was positively associated with ASA classification (P = 0.038) and operation time (P = 0.046), but negatively associated with tranexamic acid use (P = 0.001).

CONCLUSION

Patients undergoing ULIF surgery incurred a great deal of HBL. More importantly, ASA classification, operation time and tranexamic acid use were independent risk factors for HBL.

摘要

背景

隐匿性失血(HBL)在单侧双孔椎间孔镜下椎体间融合术(ULIF)中常被忽视。在本研究中,我们调查了ULIF手术中HBL的量及其影响因素。

方法

回顾性分析2020年10月至2023年11月期间100例患者的临床和影像学资料。采用Pearson或Spearman相关性分析及多元线性回归分析来确定与HBL相关的因素。

结果

平均隐匿性失血(HBL)为255.84±290.89ml,占总失血量的62.48%。相关性分析显示,HBL与美国麻醉医师协会(ASA)分级(P = 0.009)、手术时间(P = 0.004)、手术节段数(P = 0.046)及椎旁肌厚度(P = 0.043)呈正相关,但与氨甲环酸的使用呈负相关(P = 0.001)。多元线性回归分析表明,HBL与ASA分级(P = 0.038)和手术时间(P = 0.046)呈正相关,但与氨甲环酸的使用呈负相关(P = 0.001)。

结论

接受ULIF手术的患者发生大量HBL。更重要的是,ASA分级、手术时间和氨甲环酸的使用是HBL的独立危险因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b30/11657688/ce56d41fe9cb/12891_2024_8104_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b30/11657688/ce56d41fe9cb/12891_2024_8104_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7b30/11657688/ce56d41fe9cb/12891_2024_8104_Fig1_HTML.jpg

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本文引用的文献

1
"Early Efficacy and Safety of Unilateral Biportal Endoscopic Lumbar Interbody Fusion Versus Minimal Invasive in the Treatment of Lumbar Degenerative Diseases".单侧双通道内镜下腰椎间融合术与微创治疗腰椎退变性疾病的早期疗效和安全性对比
Clin Spine Surg. 2023 Oct 1;36(8):E390-E396. doi: 10.1097/BSD.0000000000001470. Epub 2023 Jun 28.
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Comparison of the total and hidden blood loss in patients undergoing single-level open and unilateral biportal endoscopic transforaminal lumbar interbody fusion: a retrospective case control study.单节段经皮与单侧双通道内镜下经椎间孔腰椎间融合术患者的总失血量和隐性失血量比较:一项回顾性病例对照研究。
BMC Musculoskelet Disord. 2023 Apr 14;24(1):295. doi: 10.1186/s12891-023-06393-y.
3
Risk factors for hidden blood loss in unilateral biportal endoscopic lumbar spine surgery.
单侧双通道内镜下腰椎手术隐匿性失血的危险因素
Front Surg. 2022 Aug 15;9:966197. doi: 10.3389/fsurg.2022.966197. eCollection 2022.
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Analysis of risk factors for perioperative hidden blood loss in unilateral biportal endoscopic spine surgery: a retrospective multicenter study.单侧双通道内镜脊柱手术围手术期隐性失血的危险因素分析:一项回顾性多中心研究。
J Orthop Surg Res. 2021 Sep 15;16(1):559. doi: 10.1186/s13018-021-02698-7.
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Percutaneous Endoscopic Transforaminal Lumbar Interbody Fusion: Technique Note and Comparison of Early Outcomes with Minimally Invasive Transforaminal Lumbar Interbody Fusion for Lumbar Spondylolisthesis.经皮内镜下经椎间孔腰椎椎间融合术:技术要点及与微创经椎间孔腰椎椎间融合术治疗腰椎滑脱早期疗效的比较
Int J Gen Med. 2021 Feb 22;14:549-558. doi: 10.2147/IJGM.S298591. eCollection 2021.
6
Comparison of Minimal Invasive Versus Biportal Endoscopic Transforaminal Lumbar Interbody Fusion for Single-level Lumbar Disease.微创与双通道内窥镜经椎间孔腰椎体间融合术治疗单节段腰椎疾病的比较。
Clin Spine Surg. 2021 Mar 1;34(2):E64-E71. doi: 10.1097/BSD.0000000000001024.
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Clinical Comparison of Unilateral Biportal Endoscopic Laminectomy versus Microendoscopic Laminectomy for Single-Level Laminectomy: A Single-Center, Retrospective Analysis.单侧双通道内镜下椎板间入路与微创经皮内镜下椎板间入路单节段椎管减压术的临床对比:一项单中心回顾性分析。
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Clin Neurol Neurosurg. 2020 Jun;193:105766. doi: 10.1016/j.clineuro.2020.105766. Epub 2020 Mar 2.