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成年重度僵硬型脊柱侧凸患者术后冠状面失衡的相关因素:一项回顾性研究

Factors associated with postoperative coronal imbalance in adult patients with severe and rigid scoliosis: a retrospective study.

作者信息

Zou Congying, Tao Luming, Zang Lei, Hai Yong

机构信息

Department of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, 5 JingYuan Road, Shijingshan District, Beijing, 100043, China.

Department of Orthopedic Surgery, Beijing Chao-Yang Hospital, Capital Medical University, 8 Gong Ti Nan Lu, Chaoyang District, Beijing, 100020, China.

出版信息

J Orthop Surg Res. 2024 Dec 18;19(1):833. doi: 10.1186/s13018-024-05328-0.

Abstract

BACKGROUND

Extensive studies examined coronal imbalance (CIB) in adolescent and adult degenerative scoliosis; however, few studies addresses on CIB in adult with severe rigid scoliosis (SRS). Therefore, we analyzed postoperative SRS patients to identify factors associated with postoperative CIB.

METHODS

In this retrospective study, we investigated SRS patients undergoing one-stage posterior column osteotomy (PCO) and fusion at our hospital between August 2012 and January 2019. The preoperative, postoperative and follow-up whole-spine anteroposterior (AP) radiographs were evaluated. Potential risk factors for postoperative CIB were analyzed using the LASSO regression, and independent risk factors were identified using binary logistic regression. A nomogram prediction model was constructed and validated.

RESULTS

Ninety eligible SRS patients were included. Postoperative radiographs showed a main curve correction rate of 54.17 ± 14.02%; however, follow-up CIB persisted in 26.67% of patients. Three independent variables affecting follow-up CIB were identified by LASSO regression, including preoperative CIB+ [OR = 12.414 (95% CI: 2.228, 69.162), P = 0.004], major curve flexibility index < 10% [OR = 14.300 (95% CI: 2.200, 92.957), P = 0.005], and immediate postoperative CIB [OR = 5.169 (95% CI: 1.387, 19.263), P = 0.014]. ROC and DCA analysis demonstrated that the nomogram had good predictive performance.

CONCLUSIONS

Preoperative CIB+, major curve flexibility index < 10%, and immediate postoperative CIB were significantly associated with postoperative CIB. These findings offer valuable guidance to improve surgical outcomes and reduce complications.

摘要

背景

广泛的研究探讨了青少年和成人退变性脊柱侧凸中的冠状面失衡(CIB);然而,针对重度僵硬性脊柱侧凸(SRS)成人患者的CIB研究较少。因此,我们分析了接受手术的SRS患者,以确定与术后CIB相关的因素。

方法

在这项回顾性研究中,我们调查了2012年8月至2019年1月期间在我院接受一期后路脊柱截骨术(PCO)和融合术的SRS患者。对术前、术后及随访时的全脊柱前后位(AP)X线片进行评估。使用LASSO回归分析术后CIB的潜在危险因素,并使用二元逻辑回归确定独立危险因素。构建并验证了列线图预测模型。

结果

纳入了90例符合条件的SRS患者。术后X线片显示主弯矫正率为54.17±14.02%;然而,26.67%的患者随访时仍存在CIB。通过LASSO回归确定了影响随访CIB的三个独立变量,包括术前CIB+[比值比(OR)=12.414(95%置信区间:2.228,69.162),P=0.004]、主弯柔韧性指数<10%[OR=14.300(95%置信区间:2.200,92.957),P=0.005]和术后即刻CIB[OR=5.169(95%置信区间:1.387,19.263),P=0.014]。受试者工作特征曲线(ROC)和决策曲线分析(DCA)表明列线图具有良好的预测性能。

结论

术前CIB+、主弯柔韧性指数<10%和术后即刻CIB与术后CIB显著相关。这些发现为改善手术效果和减少并发症提供了有价值的指导。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3076/11656543/af1226b6fa37/13018_2024_5328_Fig1_HTML.jpg

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