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青少年特发性脊柱侧凸中杂交与全椎弓根螺钉固定的比较:临床和影像学结果的荟萃分析。

Hybrid vs all pedicle screws constructs in adolescent idiopathic scoliosis: a metaanalysis of clinical and radiological outcomes.

机构信息

Department of Orthopedic Surgery, Brown University, Providence, RI, 02906, USA.

Faculty of Medicine, School of Medicine, Saint Joseph University, Beirut, Lebanon.

出版信息

Spine Deform. 2024 Sep;12(5):1229-1239. doi: 10.1007/s43390-024-00886-z. Epub 2024 Apr 29.

Abstract

BACKGROUND

Adolescent idiopathic scoliosis (AIS) affects around 1 to 3% of young individuals, leading to spinal deformities typically exceeding a Cobb angle of 10 degrees without congenital or neuromuscular causes. Advances in treatment now include various surgical techniques such as posterior fusion utilizing all-pedicle screw constructs or hybrid constructs.

METHODS

PubMed, Cochrane, and Google Scholar (pages 1-20) were searched up until February 2024. Comparative studies in which the cohort was separated into two groups (HC and PSC) were included. Data consisting of, surgery-related outcomes, sagittal radiographic outcomes, coronal radiographic outcomes, and patient-reported outcomes, was extracted and compared.

RESULTS

Twenty-eight studies including 3435 patients were included. Higher rates of complications (Odds-Ratio = 1.99, p < 0.00001) and reoperations (Odds-Ratio = 2.82, p < 0.00001) were seen in the hybrid group. Better radiographic coronal correction was seen in the PSC group in both the major curve (Mean Difference = 5.97, p < 0.00001) and the secondary curve (Mean Difference = - 10.73, p < 0.0001). However, restoration of sagittal alignment was better in the HC group when assessing thoracic kyphosis (Mean Difference = 2.97, p = 0.02) and lumbar lordosis (Mean Difference = 3.17, p = 0.005).

CONCLUSION

While all-pedicle screw constructs demonstrated greater stability in AIS compared to hybrid constructs, resulting in reduced rates of reoperations and complications, as well as improved correction of major and secondary curves, they were unable to fully restore optimal sagittal alignment.

摘要

背景

青少年特发性脊柱侧凸(AIS)影响约 1%至 3%的年轻人,导致脊柱畸形通常超过 Cobb 角 10 度,无先天性或神经肌肉原因。目前的治疗进展包括各种手术技术,如后路融合使用全椎弓根螺钉结构或混合结构。

方法

截至 2024 年 2 月,在 PubMed、Cochrane 和 Google Scholar(第 1-20 页)上进行了搜索。纳入将队列分为两组(HC 和 PSC)的比较研究。提取并比较了包括手术相关结果、矢状位影像学结果、冠状位影像学结果和患者报告结果在内的数据。

结果

共纳入 28 项研究,包括 3435 例患者。混合组的并发症发生率(优势比=1.99,p<0.00001)和再次手术率(优势比=2.82,p<0.00001)均较高。PSC 组在主要曲线(均数差=5.97,p<0.00001)和次要曲线(均数差=-10.73,p<0.0001)的冠状位影像学矫正方面更好。然而,在评估胸椎后凸(均数差=2.97,p=0.02)和腰椎前凸(均数差=3.17,p=0.005)时,HC 组在矢状位排列的恢复方面更好。

结论

虽然全椎弓根螺钉结构在 AIS 中比混合结构具有更高的稳定性,导致再次手术和并发症的发生率降低,以及主要和次要曲线的矫正改善,但它们无法完全恢复最佳矢状位排列。

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