Kofoed H, Kamby C, Anagnostaki L
Surg Gynecol Obstet. 1985 Feb;160(2):124-7.
Fifteen patients with aggressive fibromatosis are presented. The patients ranged in age from one to 64 years, an average of 26 years, and the median time of follow-up study after treatment was ten years (a range of 2.5 to 22.0). Within this period, 60 per cent (nine of 15) of the tumors recurred. In a survey of the literature, when simple excision was compared with wide extirpation, the latter was found significantly superior (p less than 0.01) in terms of limiting a recurrence of the tumor. The results of a pathoanatomic study found that the number of mast cells and the size of the primary tumor could not prognosticate the clinical course. It was concluded that aggressive fibromatosis should be evaluated and treated like a low malignant soft tissue tumor.
本文报告了15例侵袭性纤维瘤病患者。患者年龄从1岁至64岁不等，平均年龄26岁，治疗后随访研究的中位时间为10年（范围为2.5至22.0年）。在此期间，60%（15例中的9例）的肿瘤复发。在一项文献调查中，当将单纯切除与广泛切除进行比较时，发现后者在限制肿瘤复发方面明显更优（p<0.01）。病理解剖学研究结果发现，肥大细胞数量和原发肿瘤大小无法预测临床病程。得出的结论是，侵袭性纤维瘤病应像低恶性软组织肿瘤一样进行评估和治疗。
