侵袭性纤维瘤病的管理
Management of aggressive fibromatosis.
作者信息
Zhang Zhijun, Shi Jian, Yang Tao, Liu Tongjun, Zhang Kai
机构信息
Department of Colorectal and Anal Surgery, The Second Hospital of Jilin University, Changchun, Jilin 130012, P.R. China.
出版信息
Oncol Lett. 2021 Jan;21(1):43. doi: 10.3892/ol.2020.12304. Epub 2020 Nov 17.
Abstract
Aggressive fibromatosis or desmoid tumor is a rare disease resulting from fibroblasts which do not metastasize. However, desmoid tumors belong to low-grade malignant tumors since they have high potential to infiltrate surrounding tissues, causing high local recurrence rates and may affect surrounding organs, threatening life quality and expectancy. Although surgery, watch and wait, radiotherapy, chemotherapy, high intensity focused ultrasound, ablation techniques or several agents have all been frequently investigated for the treatment of this type of disease, none are deemed as standard therapy for high recurrence rates that have been supported by any data. The present review retrieved literature on treatment options for desmoids to summarize the latest treatment modalities and refine their efficacy, as well as their side effects, in order to provide a more comprehensive treatment reference for clinicians.
摘要
侵袭性纤维瘤病或韧带样瘤是一种由不发生转移的成纤维细胞引起的罕见疾病。然而，韧带样瘤属于低度恶性肿瘤，因为它们具有很高的浸润周围组织的潜力，导致局部复发率高，并且可能影响周围器官，威胁生活质量和预期寿命。尽管手术、观察等待、放疗、化疗、高强度聚焦超声、消融技术或几种药物都经常被研究用于治疗这类疾病，但由于高复发率，没有一种被视为有任何数据支持的标准疗法。本综述检索了关于韧带样瘤治疗选择的文献，以总结最新的治疗方式，并细化其疗效以及副作用，以便为临床医生提供更全面的治疗参考。
相似文献
1
Management of aggressive fibromatosis.侵袭性纤维瘤病的管理
Oncol Lett. 2021 Jan;21(1):43. doi: 10.3892/ol.2020.12304. Epub 2020 Nov 17.
2
Desmoid fibromatosis: interventional radiology (sometimes) to the rescue for an atypical disease.硬纤维瘤病：介入放射学（有时）可为一种罕见疾病提供救治。
Br J Radiol. 2025 Jun 1;98(1170):840-850. doi: 10.1093/bjr/tqae128.
3
Intra-Abdominal and Abdominal Wall Desmoid Fibromatosis.腹内及腹壁硬纤维瘤病
Oncol Ther. 2016;4(1):57-72. doi: 10.1007/s40487-016-0017-z. Epub 2016 Feb 3.
4
Optimal therapy for desmoid tumors: current options and challenges for the future.韧带样型纤维瘤病的最佳治疗方法：当前的选择及未来的挑战。
Expert Rev Anticancer Ther. 2015;15(12):1443-58. doi: 10.1586/14737140.2015.1096203. Epub 2015 Oct 15.
5
Desmoid-Type Fibromatosis: Evolving Treatment Standards.韧带样型纤维瘤病：不断发展的治疗标准
Surg Oncol Clin N Am. 2016 Oct;25(4):803-26. doi: 10.1016/j.soc.2016.05.010. Epub 2016 Aug 5.
6
The Evolving Management of Desmoid Fibromatosis.韧带样纤维瘤病的管理进展
Surg Clin North Am. 2022 Aug;102(4):667-677. doi: 10.1016/j.suc.2022.05.005.
7
Effective high intensity focused ultrasound treatment in recurrent aggressive breast fibromatosis: a case report.复发性侵袭性乳腺纤维瘤病的有效高强度聚焦超声治疗：一例报告
Onco Targets Ther. 2019 Jul 2;12:5251-5256. doi: 10.2147/OTT.S202933. eCollection 2019.
8
Is MR-guided High-intensity Focused Ultrasound a Feasible Treatment Modality for Desmoid Tumors?磁共振引导下高强度聚焦超声是治疗硬纤维瘤的一种可行治疗方式吗？
Clin Orthop Relat Res. 2016 Mar;474(3):697-704. doi: 10.1007/s11999-015-4364-0.
9
High-intensity focused ultrasound treatment for intra-abdominal desmoid tumors: a report of four cases.高强度聚焦超声治疗腹腔内硬纤维瘤：4例报告
J Med Ultrason (2001). 2016 Apr;43(2):279-84. doi: 10.1007/s10396-015-0682-9. Epub 2015 Oct 27.
10
What is the best front-line approach in patients with desmoid fibromatosis? - A retrospective analysis from a reference center.患有硬纤维瘤病的患者的最佳一线治疗方法是什么？——来自参考中心的回顾性分析。
Eur J Surg Oncol. 2021 Oct;47(10):2602-2608. doi: 10.1016/j.ejso.2021.05.002. Epub 2021 May 11.
引用本文的文献
1
Challenges in Diagnosing Adolescent Goiter: A Case Report with Brief Literature Insights in Juvenile Desmoid-Type Fibromatosis of the Thyroid Gland.青少年甲状腺肿诊断中的挑战：一例报告及甲状腺幼年型硬纤维瘤病的文献简述
J Clin Med. 2025 Jan 18;14(2):610. doi: 10.3390/jcm14020610.
2
Diaphragmatic Fibromatosis: A Diagnostic and Therapeutic Challenge: A Case Report and Review of the Literature.膈肌纤维瘤病：诊断与治疗挑战：一例报告及文献复习
J Chest Surg. 2024 Nov 5;57(6):547-552. doi: 10.5090/jcs.24.054. Epub 2024 Oct 22.
3
Aggressive fibromatosis of the sigmoid colon: A case report.乙状结肠侵袭性纤维瘤病：一例报告。
World J Gastrointest Oncol. 2024 Aug 15;16(8):3716-3722. doi: 10.4251/wjgo.v16.i8.3716.
4
Initial treatment for surgery-naïve desmoid tumors by high intensity focused ultrasound.高强度聚焦超声对未接受过手术治疗的硬纤维瘤的初始治疗
Front Oncol. 2024 Jul 22;14:1388302. doi: 10.3389/fonc.2024.1388302. eCollection 2024.
5
Case report: Rapidly progressive desmoid tumor after surgery for esophagogastric junction cancer and slowly progressive primary desmoid tumor: a report of two cases and literature review.病例报告：食管胃交界癌手术后快速进展的硬纤维瘤病和缓慢进展的原发性硬纤维瘤病：两例报告及文献复习
Front Oncol. 2024 May 10;14:1401839. doi: 10.3389/fonc.2024.1401839. eCollection 2024.
6
Annotating the Role of F-FDG PET/CT in Fibromatoses: A Benign Masquerader of Malignancies-Is It Really an Advantageous Tool?阐述F-FDG PET/CT在纤维瘤病中的作用：恶性肿瘤的良性伪装者——它真的是一种有用的工具吗？
Nucl Med Mol Imaging. 2024 May;58(3):140-146. doi: 10.1007/s13139-024-00846-5. Epub 2024 Feb 14.
7
Current Treatment Concepts for Extra-Abdominal Desmoid-Type Fibromatosis: A Narrative Review.腹外硬纤维瘤型纤维瘤病的当前治疗理念：一项叙述性综述
Cancers (Basel). 2024 Jan 8;16(2):273. doi: 10.3390/cancers16020273.
8
A Sporadic Giant Mesenteric Desmoid-Type Fibromatosis in a Teenage Female: A Report of a Rare Case.一名青少年女性的散发性巨大肠系膜硬纤维瘤病：一例罕见病例报告
Cureus. 2023 Sep 27;15(9):e46087. doi: 10.7759/cureus.46087. eCollection 2023 Sep.
9
Unusual Presentation of an Uncommon Malignancy: A 74-Year-Old Woman with Aggressive Fibromatosis of the Large Intestine Presenting as a Liver Mass and the Therapeutic Management.不常见恶性肿瘤的不常见表现：一例以肝脏肿块为表现的 74 岁老年女性侵袭性纤维瘤病及治疗管理。
Am J Case Rep. 2023 Oct 9;24:e939862. doi: 10.12659/AJCR.939862.
10
Extra‑abdominal recurrent aggressive fibromatosis: A case series and a literature review.腹外复发性侵袭性纤维瘤病：病例系列及文献综述
Mol Clin Oncol. 2023 Sep 7;19(4):84. doi: 10.3892/mco.2023.2680. eCollection 2023 Oct.
本文引用的文献
1
Efficacy of low-dose chemotherapy with methotrexate and vinblastine for patients with extra-abdominal desmoid-type fibromatosis: a systematic review.甲氨蝶呤和长春碱联合低剂量化疗治疗腹腔外韧带样型纤维瘤病患者的疗效：系统评价。
Jpn J Clin Oncol. 2020 Apr 7;50(4):419-424. doi: 10.1093/jjco/hyz204.
2
Effective high intensity focused ultrasound treatment in recurrent aggressive breast fibromatosis: a case report.复发性侵袭性乳腺纤维瘤病的有效高强度聚焦超声治疗：一例报告
Onco Targets Ther. 2019 Jul 2;12:5251-5256. doi: 10.2147/OTT.S202933. eCollection 2019.
3
Percutaneous cryoablation for the treatment of extra-abdominal desmoid tumors.经皮冷冻消融治疗腹腔外韧带样瘤。
J Surg Oncol. 2019 Sep;120(3):366-375. doi: 10.1002/jso.25597. Epub 2019 Jun 24.
4
Autophagy inhibition overcomes sorafenib resistance in S45F-mutated desmoid tumors.自噬抑制可克服 S45F 突变型硬纤维瘤对索拉非尼的耐药性。
Cancer. 2019 Aug 1;125(15):2693-2703. doi: 10.1002/cncr.32120. Epub 2019 Apr 12.
5
Targeted therapy of desmoid-type fibromatosis: mechanism, current situation, and future prospects.靶向治疗韧带样型纤维瘤病：机制、现状与未来展望。
Front Med. 2019 Aug;13(4):427-437. doi: 10.1007/s11684-018-0672-6. Epub 2019 Feb 22.
6
[Resection of a Desmoid Tumor Originating from the Greater Omentum after Surgery for Colon Cancer and Liver Metastasis-A Case Report].
Gan To Kagaku Ryoho. 2018 Dec;45(13):2444-2446.
7
Abnormal Presentation of Aggressive Fibromatosis After Radiotherapy for Keloids: Case Report and Brief Literature Review.瘢痕疙瘩放疗后侵袭性纤维瘤病的异常表现：病例报告及文献简要综述
Ann Plast Surg. 2019 Jul;83(1):104-107. doi: 10.1097/SAP.0000000000001675.
8
Long-Term Outcomes for Patients With Desmoid Fibromatosis Treated With Radiation Therapy: A 10-Year Update and Re-evaluation of the Role of Radiation Therapy for Younger Patients.接受放射治疗的硬纤维瘤患者的长期疗效：10 年随访结果更新和对年轻患者放射治疗作用的再评估。
Int J Radiat Oncol Biol Phys. 2019 Apr 1;103(5):1167-1174. doi: 10.1016/j.ijrobp.2018.12.012. Epub 2018 Dec 12.
9
Role of Nonsteroidal Anti-inflammatory Drug in Treatment of Extra-abdominal Desmoid Tumors.非甾体抗炎药在治疗腹外硬纤维瘤中的作用
Clin Orthop Surg. 2018 Jun;10(2):225-233. doi: 10.4055/cios.2018.10.2.225. Epub 2018 May 18.
10
Systematic Review of Clinical Outcomes Following Various Treatment Options for Patients with Extraabdominal Desmoid Tumors.系统评价各种治疗方案治疗腹外型硬纤维瘤患者的临床结局。
Ann Surg Oncol. 2018 Jun;25(6):1544-1554. doi: 10.1245/s10434-018-6408-7. Epub 2018 Apr 11.
Zotero 插件