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警报系统及家庭护理伙伴支持对预防术后谵妄的可行性

Feasibility of Alerting Systems and Family Care Partner Support for Postoperative Delirium Prevention.

作者信息

Vlisides Phillip E, Runstadler Nathan, Martinez Selena, Ragheb Jacqueline W, Mentz Graciela, Leis Aleda, Schoettinger Amanda, Hickey Kimberly, McKinney Amy, Brooks Joseph, Zierau Mackenzie, Norcott Alexandra, Mody Lona, Inouye Sharon K, Avidan Michael S, Min Lillian

机构信息

Department of Anesthesiology, Michigan Medicine, Ann Arbor, MI.

Center for Consciousness Science, University of Michigan Medical School, Ann Arbor, MI.

出版信息

J Neurosurg Anesthesiol. 2024 Dec 19. doi: 10.1097/ANA.0000000000001016.

Abstract

BACKGROUND

The objective of this study was to determine whether postoperative pager alerts to the Hospital Elder Life Program (HELP), a delirium prevention service, would accelerate program enrollment for older surgical patients. This study also tested feasibility of family care partner interventions for delirium prevention.

METHODS

This single-center, pilot clinical trial factorially randomized 57 non-cardiac surgical patients ≥70 years of age to 4 arms: (1) standard care, (2) pager alerts to accelerate HELP enrollment, (3) family care partner-based delirium prevention interventions, or (4) a combined arm with both HELP and family interventions. The primary clinical outcome was delirium (assessed through the Confusion Assessment Method).

RESULTS

In the pager alerting arms, 13/24 (54%) participants were enrolled by HELP on postoperative day 1 compared with 0/26 (0%, P<0.001) in the non-alerting arms. Median [interquartile range] time spent in delirium prevention protocols was significantly longer in pager alerting arms than in non-alerting arms (39 [5 to 75] min vs. 0 [0 to 0] min; P<0.001). Family care partners spent 18 [11 to 25)] hours at the bedside over the first 3 postoperative days. There was no significant difference in delirium occurrence in participants randomized to pager alert arms compared with non-alerting arms (odds ratio, 1.02, 95% CI, 0.97-1.07; P=0.390). Similarly, there was no significant difference in delirium occurrence in family intervention arms compared with nonintervention arms (odds ratio, 0.97; 95% CI 0.93-10.02; P=0.270).

CONCLUSIONS

Pager alerts significantly reduced time to HELP enrollment, albeit without reducing delirium incidence in this pilot study. Family care partners spent substantial time at the bedside during the study period.

摘要

背景

本研究的目的是确定术后通过传呼机向谵妄预防服务机构——医院老年生活项目(HELP)发出警报,是否会加快老年外科患者加入该项目的速度。本研究还测试了家庭护理伙伴干预措施预防谵妄的可行性。

方法

这项单中心试点临床试验将57名年龄≥70岁的非心脏外科手术患者按因素随机分为4组:(1)标准护理组;(2)通过传呼机发出警报以加快加入HELP项目的组;(3)基于家庭护理伙伴的谵妄预防干预组;(4)同时包含HELP和家庭干预的联合组。主要临床结局是谵妄(通过混乱评估方法进行评估)。

结果

在传呼机警报组中,13/24(54%)的参与者在术后第1天被HELP项目录取,而非警报组中这一比例为0/26(0%,P<0.001)。传呼机警报组在谵妄预防方案中花费的中位[四分位间距]时间显著长于非警报组(39[5至75]分钟 vs. 0[0至0]分钟;P<0.001)。家庭护理伙伴在术后的前3天内在床边陪伴的时间为18[11至25]小时。与非警报组相比,随机分配到传呼机警报组的参与者发生谵妄的情况无显著差异(优势比,1.02,95%可信区间,0.97 - 1.07;P = 0.390)。同样,与非干预组相比,家庭干预组参与者发生谵妄的情况也无显著差异(优势比,0.97;95%可信区间0.93 - 10.02;P = 0.270)。

结论

在这项试点研究中,传呼机警报显著缩短了加入HELP项目的时间,尽管并未降低谵妄发生率。在研究期间,家庭护理伙伴在床边陪伴了大量时间。

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