• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

冷冻疗法局部麻醉对磨牙切端矿化不全牙齿的疗效:一项随机对照试验。

Efficacy of local anesthesia with cryotherapy on teeth with molar incisal hypomineralization: a randomized control trial.

作者信息

Peedikayil Faizal C, Kottayi Soni, Aravind Athira, Sreedharan Aswathi, Ramesh Athul

机构信息

Department of Pediatric and Preventive Dentistry, Kannur Dental College, Kannur, Kerala, India.

出版信息

J Dent Anesth Pain Med. 2024 Dec;24(6):385-393. doi: 10.17245/jdapm.2024.24.6.385. Epub 2024 Nov 26.

DOI:10.17245/jdapm.2024.24.6.385
PMID:39697191
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11650453/
Abstract

BACKGROUND

Tooth hypersensitivity presents a significant clinical challenge in managing molar-incisal hypomineralization (MIH), potentially compromising the effectiveness of restorative treatments. Cryotherapy has emerged as a promising approach to reduce pain and inflammation. This study aimed to evaluate and compare the effects of cryotherapy as an adjuvant to nerve blocks in reducing operative pain and sensitivity in patients.

METHODS

A split-mouth randomized controlled trial was conducted in 28 patients with MIH of the right and left lower molars. ie, 56 teeth. Group (1) control group (n = 28) was administered an Inferior Alveolar Nerve block and group (2) was administered cryotherapy spray after the Inferior Alveolar Nerve block. The Visual Analog Scale (VAS) and Legs, Activity, Cry, Consolability (FLACC) scales were used to compare intraoperative pain. The Mann-Whitney U test was used to test the significance across the study groups, and the chi-square test was used to compare success rates between the two groups; a value of less than 0.05 was considered significant.

RESULTS

For VAS scale, the mean value in Group A is 8.89 ± 0.79, whereas in Group B, the values are 4.71 ± 1.46. For the FLACC scale, Group A scores were 7.14 ± 1.04, and Group B scores were 4.48 ± 1.37. When intergroup values were compared, the FLACC and VAS scores were statistically significant at P < 0.001.

CONCLUSION

Within the limitations of this study, applying cryotherapy to tooth surfaces following an Inferior Alveolar Nerve block effectively reduces pain and sensitivity in teeth affected by MIH.

摘要

背景

牙齿过敏在磨牙-切牙低矿化(MIH)的治疗中是一个重大的临床挑战,可能会影响修复治疗的效果。冷冻疗法已成为一种有前景的减轻疼痛和炎症的方法。本研究旨在评估和比较冷冻疗法作为神经阻滞辅助手段对减轻患者手术疼痛和敏感性的效果。

方法

对28例左右下颌磨牙患有MIH的患者进行了一项双盲随机对照试验,即56颗牙齿。第(1)组为对照组(n = 28),接受下牙槽神经阻滞;第(2)组在接受下牙槽神经阻滞后给予冷冻疗法喷雾。使用视觉模拟量表(VAS)和下肢、活动、哭闹、安慰度(FLACC)量表比较术中疼痛。采用曼-惠特尼U检验来检验各研究组之间的显著性,采用卡方检验比较两组之间的成功率;P值小于0.05被认为具有显著性。

结果

对于VAS量表,A组的平均值为8.89±0.79,而B组的值为4.71±1.46。对于FLACC量表,A组的评分为7.14±1.04,B组的评分为4.48±1.37。当比较组间值时,FLACC和VAS评分在P < 0.001时具有统计学显著性。

结论

在本研究的局限性范围内,在下牙槽神经阻滞后对牙齿表面应用冷冻疗法可有效减轻受MIH影响牙齿的疼痛和敏感性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a52/11650453/ece82144bfdc/jdapm-24-385-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a52/11650453/b671e44f995f/jdapm-24-385-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a52/11650453/ece82144bfdc/jdapm-24-385-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a52/11650453/b671e44f995f/jdapm-24-385-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1a52/11650453/ece82144bfdc/jdapm-24-385-g002.jpg

相似文献

1
Efficacy of local anesthesia with cryotherapy on teeth with molar incisal hypomineralization: a randomized control trial.冷冻疗法局部麻醉对磨牙切端矿化不全牙齿的疗效:一项随机对照试验。
J Dent Anesth Pain Med. 2024 Dec;24(6):385-393. doi: 10.17245/jdapm.2024.24.6.385. Epub 2024 Nov 26.
2
Effect of photobiomodulation on the efficacy of anesthesia in maxillary permanent molar teeth with molar incisor hypomineralization: A randomized clinical trial.光生物调节对上颌第一恒磨牙伴磨牙切牙矿化不全麻醉效果的影响:一项随机临床试验
Int J Paediatr Dent. 2024 May;34(3):219-228. doi: 10.1111/ipd.13118. Epub 2023 Sep 8.
3
Cryotherapy and pain intensity during endodontic treatment of mandibular first permanent molars with symptomatic irreversible pulpitis: A randomized controlled trial.冷冻疗法与症状性不可复性牙髓炎下颌第一恒磨牙根管治疗期间疼痛强度的随机对照试验。
Clin Oral Investig. 2023 Aug;27(8):4585-4593. doi: 10.1007/s00784-023-05084-1. Epub 2023 Jun 3.
4
Enhancing pediatric comfort: a comprehensive approach to managing molar-incisor hypomineralization with preemptive analgesia and behavioral strategies.增强儿科舒适度:采用预防性镇痛和行为策略综合管理磨牙-切牙釉质发育不全。
J Clin Pediatr Dent. 2024 Nov;48(6):123-132. doi: 10.22514/jocpd.2024.096. Epub 2024 Nov 3.
5
Is SDF better than the SMART (silver modified atraumatic restorative technique) in the management of molar incisor hypomineralisation molars with initial caries?在管理患有初期龋齿的磨牙切牙矿化不全磨牙时,自酸蚀粘结剂(SDF)是否比银改良非创伤性修复技术(SMART)更好?
Evid Based Dent. 2024 Sep;25(3):162-163. doi: 10.1038/s41432-024-01062-y. Epub 2024 Sep 10.
6
Comparative study of articaine 4% versus lidocaine 2% in the local anesthesia of permanent mandibular first molars affected by MIH: a randomized controlled trial.4%阿替卡因对比 2%利多卡因用于 MIH 所致下颌第一恒磨牙局麻效果的对比研究:一项随机对照试验
Eur Arch Paediatr Dent. 2023 Oct;24(5):621-630. doi: 10.1007/s40368-023-00827-w. Epub 2023 Aug 1.
7
Sensitivity Treatments for Teeth with Molar Incisor Hypomineralization: Protocol for a Randomized Controlled Trial.磨牙切牙矿化不全牙齿的敏感性治疗:一项随机对照试验方案
JMIR Res Protoc. 2022 Jan 6;11(1):e27843. doi: 10.2196/27843.
8
Efficacy of Intraosseous Local Anesthesia for Restorative Procedures in Molar Incisor Hypomineralization-Affected Teeth in Children.骨内局部麻醉用于儿童磨牙-切牙矿化不全患牙修复治疗的疗效
Contemp Clin Dent. 2018 Sep;9(Suppl 2):S272-S277. doi: 10.4103/ccd.ccd_252_18.
9
Prevalence of Hypersensitivity in Teeth Affected by Molar-Incisor Hypomineralization (MIH).磨牙-切牙牙釉质发育不全(MIH)致牙齿过敏的流行情况。
Caries Res. 2019;53(4):424-430. doi: 10.1159/000495848. Epub 2019 Jan 24.
10
Molar incisor hypomineralization and oral health-related quality of life: a sample of 8-12-years-old children.磨牙症和牙齿矿化不全与口腔健康相关生活质量:8-12 岁儿童样本。
Clin Oral Investig. 2024 Jan 20;28(1):105. doi: 10.1007/s00784-024-05490-z.

引用本文的文献

1
Evidence mapping and quality assessment of randomised trials related to molar incisor hypomineralisation.与磨牙切牙矿化不全相关的随机试验的证据图谱绘制与质量评估
Eur Arch Paediatr Dent. 2025 Aug 24. doi: 10.1007/s40368-025-01100-y.

本文引用的文献

1
Cryotherapy in the Management of Vital Pulp: A Case Report.活髓治疗中的冷冻疗法:病例报告
Cureus. 2024 Jun 3;16(6):e61574. doi: 10.7759/cureus.61574. eCollection 2024 Jun.
2
Effect of cryoanesthesia and sweet tasting solution in reducing injection pain in pediatric patients aged 7-10 years: a randomized controlled trial.冷冻麻醉和甜味溶液对减轻7至10岁儿科患者注射疼痛的效果:一项随机对照试验。
J Dent Anesth Pain Med. 2024 Feb;24(1):37-45. doi: 10.17245/jdapm.2024.24.1.37. Epub 2024 Feb 1.
3
Comparative evaluation of the effectiveness of intracanal and intraoral cryotherapy on postendodontic pain in patients with symptomatic apical periodontitis: A randomized clinical trial.
根管内与口内冷冻疗法对有症状根尖周炎患者根管治疗后疼痛疗效的比较评估:一项随机临床试验。
J Conserv Dent Endod. 2023 Sep-Oct;26(5):555-559. doi: 10.4103/jcd.jcd_284_23. Epub 2023 Sep 16.
4
Update of the molar incisor hypomineralization: Würzburg concept.《低龄儿童恒牙龋、中龋和猖獗龋:沃茨堡概念》更新。
Eur Arch Paediatr Dent. 2023 Dec;24(6):807-813. doi: 10.1007/s40368-023-00848-5. Epub 2023 Oct 19.
5
Reliability of three pain assessment tools in children requiring dental treatment: A comparative clinical study.三种疼痛评估工具在需要牙科治疗的儿童中的可靠性:一项比较性临床研究。
J Indian Soc Pedod Prev Dent. 2023 Apr-Jun;41(2):126-132. doi: 10.4103/jisppd.jisppd_132_23.
6
Comparative evaluation of intracanal cryotherapy and curcumin as a final irrigant in reducing post endodontic pain in primary teeth.根管内冷冻疗法与姜黄素作为乳牙根管治疗后减少疼痛的最终冲洗剂的比较评价
J Indian Soc Pedod Prev Dent. 2022 Jul-Sep;40(3):297-301. doi: 10.4103/jisppd.jisppd_216_22.
7
Effect of intracanal cryotherapy on postendodontic pain: a systematic review and meta-analysis of randomized controlled trials.根管内冷冻疗法对根管治疗后疼痛的影响:一项随机对照试验的系统评价和荟萃分析
J Dent Anesth Pain Med. 2021 Feb;21(1):15-27. doi: 10.17245/jdapm.2021.21.1.15. Epub 2021 Jan 29.
8
The effect of pre-cooling versus topical anesthesia on pain perception during palatal injections in children aged 7-9 years: a randomized split-mouth crossover clinical trial.7-9岁儿童腭部注射时预冷与表面麻醉对疼痛感知的影响:一项随机分口交叉临床试验
J Dent Anesth Pain Med. 2020 Dec;20(6):377-386. doi: 10.17245/jdapm.2020.20.6.377. Epub 2020 Dec 28.
9
Use of Cryotherapy for Managing Chronic Pain: An Evidence-Based Narrative.冷冻疗法用于慢性疼痛管理:基于证据的叙述
Pain Ther. 2021 Jun;10(1):81-100. doi: 10.1007/s40122-020-00225-w. Epub 2020 Dec 14.
10
Cryotherapy: A New Paradigm of Treatment in Endodontics.冷冻疗法:牙髓病学治疗的新范例。
J Endod. 2020 Jul;46(7):936-942. doi: 10.1016/j.joen.2020.03.019. Epub 2020 May 6.