Ranković Aleksandar, Cvetanović Maja, Miladinović Jelena, Ćosić Milica, Popović Dragonjić Lidija
Department of Infectious Diseases and Epidemiology, Faculty of Medicine, University of Niš, Niš, Serbia.
Clinic for Infectology, University Clinical Center Niš, Niš, Serbia.
Front Med (Lausanne). 2024 Dec 3;11:1498971. doi: 10.3389/fmed.2024.1498971. eCollection 2024.
Acute hepatitis E virus (HEV) and malaria are not rare infections in tropical countries; however, in the European continent, such imported entity has not been reported up to now. Herein, we report a 24-year-old male suffering from malaria and hepatitis E, who was admitted with acute hepatic failure dark colored urine, followed by coagulation and inflammation parameters increase. Blood smear analysis revealed the presence of , while serological tests revealed anti-HEV IgM antibodies. After the recommended antimalarial drugs and supportive therapy, the patient survived and was discharged disease-free. Conclusions: Following WHO guidelines for the treatment of severe malaria, full recovery in patient was achieved.
急性戊型肝炎病毒（HEV）感染和疟疾在热带国家并非罕见感染；然而，在欧洲大陆，此类输入性病例至今尚未见报道。在此，我们报告一名24岁男性，患有疟疾和戊型肝炎，因急性肝衰竭伴深色尿入院，随后凝血和炎症参数升高。血液涂片分析发现疟原虫，而血清学检测显示抗HEV IgM抗体阳性。在给予推荐的抗疟药物和支持性治疗后，患者存活并康复出院。结论：遵循世界卫生组织关于重症疟疾治疗的指南，患者实现了完全康复。
