Almohamed Ahmad, Qatza Ayham, Alsamman Haifa, Hamsho Suaad, Atia Mohammad, Tamer Rahaf, Ali Almaya Mhd, Kazkz Waddah
Faculty of Medicine, Hama University, Hama, Syria.
Neurology Department, Hama National Hospital, Hama, Syria.
Radiol Case Rep. 2024 Dec 3;20(2):1211-1214. doi: 10.1016/j.radcr.2024.11.006. eCollection 2025 Feb.
Bickerstaff Brainstem Encephalitis (BBE) is a rare immunologic condition characterized by CNS inflammation, presenting with ataxia, external ophthalmoplegia, altered consciousness, and quadriplegia. A 25-year-old male with no significant medical history exhibited symptoms of blurred vision, diplopia, facial numbness, and imbalance following a respiratory infection. Brain MRI revealed hyperintense lesions in the cerebral peduncle and pons on T2-weighted/FLAIR sequences but not on T1-weighted sequences, indicative of demyelination. Lumbar puncture showed clear cerebrospinal fluid with lymphocytic pleocytosis (80 cells/μl, 95% lymphocytes) and normal protein levels. The patient was treated with intravenous methylprednisolone (1000 mg/day for five days), resulting in recovery and normal follow-up MRI findings. Early diagnosis and treatment are crucial to minimize complications and improve outcomes. Additionally, airway management is essential for patients with impaired respiratory function, and long-term rehabilitation may be necessary for those recovering from encephalitis.
比克斯特费尔德脑干脑炎（BBE）是一种罕见的免疫性疾病，其特征为中枢神经系统炎症，表现为共济失调、外展神经麻痹、意识改变和四肢瘫痪。一名无重大病史的25岁男性在呼吸道感染后出现视力模糊、复视、面部麻木和平衡失调症状。脑部MRI显示，在T2加权/液体衰减反转恢复序列上脑桥和大脑脚有高信号病变，但在T1加权序列上未见异常，提示脱髓鞘。腰椎穿刺显示脑脊液清澈，淋巴细胞增多（80个细胞/μl，95%为淋巴细胞），蛋白质水平正常。该患者接受了静脉注射甲泼尼龙治疗（1000毫克/天，共5天），最终康复，后续MRI检查结果正常。早期诊断和治疗对于减少并发症和改善预后至关重要。此外，对于呼吸功能受损的患者，气道管理至关重要，而对于从脑炎中康复的患者，可能需要长期康复治疗。
