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[2020 - 2023年墨西哥新冠疫苗安全委员会的重组，墨西哥重组新冠疫苗安全委员会，2020 - 2023年]

[Restructuring of the COVID-19 Vaccine Safety Committee 2020-2023 in MexicoReestruturação do Comitê para Segurança das Vacinas contra a COVID-19, 2020-2023, México].

作者信息

Santibañez Copado Ana María, Reyes Terán G, Váldes Fererr Sergio Iván, Pavía Ruz S Noris, Antonio Arauz, Toledo Salinas Carmen, Mosqueda Juan Luis, Fernández Patricio Ortiz, Espinosa-Santibañez Jesús Alberto, Scheffler-Mendoza Selma, Díaz Ortega José Luis, Romualdo-Tello Nadia María

机构信息

Centro Nacional para la Salud de la Infancia y Adolescencia Secretaría de Salud Ciudad de México México Centro Nacional para la Salud de la Infancia y Adolescencia, Secretaría de Salud, Ciudad de México, México.

Comisión Coordinadora de Institutos Nacionales de Salud y Hospitales de Alta Especialidad Secretaría de Salud Ciudad de México México Comisión Coordinadora de Institutos Nacionales de Salud y Hospitales de Alta Especialidad, Secretaría de Salud, Ciudad de México, México.

出版信息

Rev Panam Salud Publica. 2024 Dec 18;48:e106. doi: 10.26633/RPSP.2024.106. eCollection 2024.

DOI:10.26633/RPSP.2024.106
PMID:39697271
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11653959/
Abstract

OBJECTIVE

To describe the process of restructuring the National Expert Committee and its impact on the causality assessment of events supposedly attributable to vaccination or immunization (ESAVI) in the context of vaccine safety monitoring during the COVID-19 pandemic, 2020-2023.

METHOD

A report was prepared on the experience of creating and operating Mexico's National Expert Committee during the aforementioned period.

RESULTS

During the 2020-2023 period, 1293 severe ESAVIs were reported after COVID-19 vaccination; after 98.6% (1275) of them had been assessed and classified, 10 specialized subcommittees were formed.

CONCLUSIONS

Restructuring of the committee, assessment of adverse events with a series of prior steps, and use of the World Health Organization's causality assessment tool made it possible to generate scientific documents to validate vaccine safety and maintain trust in vaccination.

摘要

目的

描述2020 - 2023年新冠疫情期间，在疫苗安全监测背景下，国家专家委员会的重组过程及其对疑似疫苗接种或免疫所致事件（ESAVI）因果关系评估的影响。

方法

编写了一份关于上述期间墨西哥国家专家委员会创建和运作经验的报告。

结果

在2020 - 2023年期间，新冠疫苗接种后报告了1293起严重ESAVI；在对其中98.6%（1275起）进行评估和分类后，成立了10个专业小组委员会。

结论

委员会的重组、通过一系列前期步骤对不良事件进行评估以及使用世界卫生组织的因果关系评估工具，使得能够生成科学文件以验证疫苗安全性并维持对疫苗接种的信任。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11653959/fe2bb1ebb2ab/rpsp-48-e106-Figure2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11653959/e9c5bb0094d4/rpsp-48-e106-Figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11653959/fe2bb1ebb2ab/rpsp-48-e106-Figure2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11653959/e9c5bb0094d4/rpsp-48-e106-Figure1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa9d/11653959/fe2bb1ebb2ab/rpsp-48-e106-Figure2.jpg

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本文引用的文献

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Neurologic adverse events among 704,003 first-dose recipients of the BNT162b2 mRNA COVID-19 vaccine in Mexico: A nationwide descriptive study.墨西哥 704003 名第一剂 BNT162b2 mRNA COVID-19 疫苗接种者的神经不良反应：一项全国描述性研究。
Clin Immunol. 2021 Aug;229:108786. doi: 10.1016/j.clim.2021.108786. Epub 2021 Jun 18.