Mohammadi Hassan Reza, Erfani Ali, Karimiyarandy Hosein, Vasigh Amilooah, Sadeghi Sohrab, Roozegar Mohamadali
Department of Neurosurgery, School of Medicine, Imam Hossein Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
School of Medicine, Emam Khomeini Hospital, Ilam University of Medical Sciences, Ilam, Iran.
Bull Emerg Trauma. 2024;12(4):162-167. doi: 10.30476/beat.2024.103200.1523.
Laminectomy is one of the most prevalent back surgeries. Considering the importance of controlling and minimizing surgical complications, this study was conducted to determine the effect of Sevoflurane and Propofol on the state of renal complications in patients undergoing laminectomy surgery.
This clinical trial was conducted in Ilam (Iran). The study used a double-blind random sampling procedure, and the patients were divided into three groups receiving Sevoflurane (n=25), Propofol (n=25), and the combination of Sevoflurane and Propofol (n=25). The research tool included a checklist of demographic characteristics as well as a clinical examination. Kidney complications were diagnosed based on history, clinical examinations, and laboratory test results. The obtained data were analyzed using SPSS software.
In this study, the patient's mean age in the Propofol group was 52.4±5.6, the Sevoflurane group was 50.8±2.5, and Sevoflurane plus Propofol group was 53.5±3.4. The Sevoflurane plus Propofol group had the highest rate of urinary retention (n=7, 28%). In addition, there was no difference between laboratory results of creatinine and urinary retention in the studied groups (P>0.05). Besides, the comparison of the mean of renal laboratory indicators in the research patients indicated that the level of serum creatinine, and cystatin C of the patients had no significant change.
There was no significant difference between the complications in the three groups. Therefore, all three drugs can be administered to patients.
椎板切除术是最常见的脊柱手术之一。考虑到控制和最小化手术并发症的重要性，本研究旨在确定七氟醚和丙泊酚对接受椎板切除术患者肾脏并发症状态的影响。
本临床试验在伊朗伊拉姆进行。该研究采用双盲随机抽样程序，将患者分为三组，分别接受七氟醚（n = 25）、丙泊酚（n = 25）以及七氟醚与丙泊酚联合用药（n = 25）。研究工具包括人口统计学特征清单以及临床检查。根据病史、临床检查和实验室检查结果诊断肾脏并发症。使用SPSS软件对获得的数据进行分析。
在本研究中，丙泊酚组患者的平均年龄为52.4±5.6岁，七氟醚组为50.8±2.5岁，七氟醚加丙泊酚组为53.5±3.4岁。七氟醚加丙泊酚组尿潴留发生率最高（n = 7，28%）。此外，研究组间肌酐和尿潴留的实验室结果无差异（P>0.05）。此外，对研究患者肾脏实验室指标平均值的比较表明，患者血清肌酐和胱抑素C水平无显著变化。
三组并发症之间无显著差异。因此，这三种药物均可用于患者。
