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一头野兽的复苏:2000年至2024年密苏里州梅毒管理与控制面临的挑战

Revival of a Beast: The Challenges Facing the Management and Control of Syphilis in Missouri from 2000 to 2024.

作者信息

Abdessamad Hilal, Jamaleddine Wassim, Rojas-Moreno Christian, Dandachi Dima

机构信息

Division of Infectious Diseases, Department of Internal Medicine, University of Missouri-Columbia, Columbia, Missouri.

Division of Infectious Diseases, Department of Internal Medicine, University of Missouri-Columbia, Columbia, Missouri and he is also the Medical Director of Columbia/Boone County Public Health & Human Services, Columbia, Missouri.

出版信息

Mo Med. 2024 Nov-Dec;121(6):474-480.

PMID:39697571
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11651269/
Abstract

Syphilis is an old disease that remains to be a major threat in the modern world. In the last decade, we have seen an exponential rise in the number of new cases. While this surge is universal, some places appear to be more affected than others, such as the southern and midwestern states in the United States. In Missouri, the syphilis epidemic strikes almost everywhere, from rural to metropolitan areas, affecting various age groups and subpopulations. We conducted this narrative review focusing on published data regarding syphilis in Missouri, and discussing contemporary risk factors for such an unprecedented spread, and treatment and prevention options. While rurality, social stigma, and medication shortage play a role in this disease spread, new plans are being adopted in the state for mitigation of its burden.

摘要

梅毒是一种古老的疾病,在现代世界仍然是一个重大威胁。在过去十年中,我们看到新病例数量呈指数级增长。虽然这种激增是全球性的,但有些地方似乎比其他地方受影响更严重,比如美国南部和中西部各州。在密苏里州,梅毒疫情几乎在各地爆发,从农村到城市地区,影响着各个年龄组和亚人群。我们进行了这项叙述性综述,重点关注密苏里州梅毒的已发表数据,并讨论这种前所未有的传播的当代风险因素以及治疗和预防方案。虽然农村地区、社会耻辱感和药物短缺在这种疾病传播中起了作用,但该州正在采取新的计划来减轻其负担。

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本文引用的文献

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Sex Transm Dis. 2021 Sep 1;48(9):615-619. doi: 10.1097/OLQ.0000000000001395.
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The Emerging Intersection Between Injection Drug Use and Early Syphilis in Nonurban Areas of Missouri, 2012-2018.2012-2018 年,密苏里州非城市地区注射吸毒与早期梅毒之间的新兴交集。
J Infect Dis. 2020 Sep 2;222(Suppl 5):S465-S470. doi: 10.1093/infdis/jiaa056.