Mazzella-Ebstein AnnMarie, Barton-Burke Margaret, Anthony Venice, White Charlie, Zhang Zhigang, Smith Andrea, Robson Mark
Nursing Research, Memorial Sloan Kettering Cancer Center, New York, USA.
Breast and Imaging Center, Memorial Sloan Kettering Cancer, New York, USA.
Asia Pac J Oncol Nurs. 2024 Oct 15;11(12):100604. doi: 10.1016/j.apjon.2024.100604. eCollection 2024 Dec.
Test the feasibility and effectiveness of a text message reminder intervention for the self-management of oral anticancer medication in patients with metastatic breast cancer.
Forty-three females initiating treatment with palbociclib participated in a two-armed prospective randomized clinical trial. Participants were randomized into the control ( = 21) and intervention groups ( = 22) from January 2020 to January 2023. Survey responses were collected at three-time points; (1) at consent, (2) end of treatment cycles, and (3) at a follow-up clinic visit. Surveys included a demographic questionnaire, the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire, post-study assessment, and the R-15 Participant Satisfaction Questionnaire. Nurse providers completed the Adaptation of Stamps Nurse Workload questionnaire.
The COVID-19 pandemic and regulatory decisions supporting other CDK4/6 medications negatively influence recruitment; thus, a small sample for each arm only detected large differences between the two arms regarding effectiveness. Feasibility analysis was not conducted due to insufficient data, but the participants frequently used their smartphones for text messaging. Although the survey data were limited, participants provided anecdotal information supporting the use of text messaging as a positive method to remind them to take their medication, have their labs drawn, and attend MD visits. Participants would have liked text messages at the exact time they took their medications as a simple reminder.
Given the importance of cancer treatments and the difficulties patients experience during these treatments, text messages using smartphones can actively improve patients' engagement and their ability to manage their treatment regimens.
ClinicalTrials.gov; ID: NCT04216576.
测试短信提醒干预措施对转移性乳腺癌患者口服抗癌药物自我管理的可行性和有效性。
43名开始使用哌柏西利治疗的女性参与了一项双臂前瞻性随机临床试验。从2020年1月至2023年1月，参与者被随机分为对照组（n = 21）和干预组（n = 22）。在三个时间点收集调查回复；（1）同意参与时，（2）治疗周期结束时，以及（3）在后续门诊就诊时。调查包括一份人口统计学问卷、欧洲癌症研究与治疗组织生活质量问卷、研究后评估以及R - 15参与者满意度问卷。护士提供者完成了邮票护士工作量问卷的改编版。
COVID - 19大流行以及支持其他CDK4/6药物的监管决定对招募产生了负面影响；因此，每组的小样本仅检测到两组在有效性方面的巨大差异。由于数据不足未进行可行性分析，但参与者经常使用智能手机进行短信收发。尽管调查数据有限，但参与者提供了轶事信息，支持将短信作为一种积极的方法来提醒他们服药、进行实验室检查以及就诊。参与者希望在服药的确切时间收到短信作为简单提醒。
鉴于癌症治疗的重要性以及患者在这些治疗过程中所经历的困难，使用智能手机发送短信可以积极提高患者的参与度及其管理治疗方案的能力。
ClinicalTrials.gov；标识符：NCT04216576。
