Peng Yao, Wang Mengyu, Zhou Changyu, Li Zhenpeng, Li Zhe, Zhang Yuan, Kan Biao, Luo Ming, Lu Xin
National Key Laboratory of Intelligent Tracking and Forecasting for Infectious Diseases, National Institute for Communicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan City, Shandong Province, China.
China CDC Wkly. 2024 Nov 22;6(47):1236-1241. doi: 10.46234/ccdcw2024.248.
WHAT IS ALREADY KNOWN ABOUT THIS TOPIC?: The emergence of rare multidrug-resistant serovars is increasingly common in developing countries, posing a significant public health risk.
WHAT IS ADDED BY THIS REPORT?: This report identified five rare serovars in China for the first time and using whole-genome sequencing, identified their hidden spread among healthy individuals. Additionally, antibiotic resistance genes and virulence genes were identified.
WHAT ARE THE IMPLICATIONS FOR PUBLIC HEALTH PRACTICE?: Healthy individuals, especially food handlers, may be sources of hidden dissemination. Therefore, monitoring prevalence in healthy individuals is important for understanding and managing the risks of foodborne illness.
关于该主题已知的信息有哪些？：在发展中国家，罕见的多重耐药血清型的出现日益普遍，构成了重大的公共卫生风险。
本报告新增了哪些内容？：本报告首次在中国鉴定出五种罕见血清型，并通过全基因组测序确定了它们在健康个体中的隐匿传播情况。此外，还鉴定出了抗生素抗性基因和毒力基因。
对公共卫生实践有何启示？：健康个体，尤其是食品处理人员，可能是隐匿传播的源头。因此，监测健康个体中的流行情况对于理解和管理食源性疾病风险至关重要。
