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小儿全身麻醉期间的术中ST段压低:肥厚型心肌病的早期检测

Intraoperative ST Segment Depression During General Anesthesia in a Child: Early Detection of Hypertrophic Cardiomyopathy.

作者信息

Gadelsayed Joshua, Wani Tariq, Rehman Saif, Tobias Joseph D

机构信息

Ohio University Heritage College of Osteopathic Medicine, Athens, OH, USA.

Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, OH, USA.

出版信息

Cardiol Res. 2024 Dec;15(6):467-471. doi: 10.14740/cr1722. Epub 2024 Nov 7.

Abstract

Continuous electrocardiographic (ECG) monitoring remains crucial during surgery in infants and children. Although generally uncommon in pediatric-aged patients, ECG changes may occasionally be indicative of a variety of myocardial pathologies including anomalous origin of coronary arteries, ventricular hypertrophy, myocarditis, hypothermia, drug effects, electrolyte abnormalities, acid-base disturbances or conduction system disorders such as Wolff-Parkinson-White and Brugada syndrome. Distinguishing between pathologic and non-pathologic conditions impacting the ECG must be considered so that appropriate interventions are provided to prevent perioperative morbidity and mortality. We report a case of a 2-year-old child who exhibited ST segment depression and increased R wave amplitude during general anesthesia. Although the anesthetic care was uneventful and the patient was otherwise asymptomatic, immediate postoperative workup including echocardiogram revealed previously undiagnosed hypertrophic cardiomyopathy. The occurrence of intraoperative ST-T wave changes in this patient underscores the need for a high index of suspicion for underlying cardiac pathology, even in the absence of overt clinical manifestations. This case highlights the importance of intraoperative ECG monitoring in pediatric patients, explores the causes of ST-T wave changes, reviews similar cases in the literature, and proposes a pathway for perioperative evaluation.

摘要

在婴幼儿及儿童手术期间,持续心电图(ECG)监测仍然至关重要。虽然在儿科患者中一般不常见,但ECG变化偶尔可能提示多种心肌病变,包括冠状动脉异常起源、心室肥厚、心肌炎、体温过低、药物作用、电解质异常、酸碱平衡紊乱或传导系统疾病,如预激综合征和布加综合征。必须考虑区分影响ECG的病理性和非病理性情况,以便采取适当干预措施预防围手术期发病和死亡。我们报告一例2岁儿童,在全身麻醉期间出现ST段压低和R波振幅增加。尽管麻醉过程顺利且患者无其他症状,但术后立即进行的包括超声心动图在内的检查显示存在先前未诊断出的肥厚型心肌病。该患者术中ST-T波变化的发生强调,即使没有明显临床表现,也需要对潜在心脏病变保持高度怀疑。本病例突出了小儿患者术中ECG监测的重要性,探讨了ST-T波变化的原因,回顾了文献中的类似病例,并提出了围手术期评估的途径。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/883e/11650574/9b4d1a7463bc/cr-15-467-g001.jpg

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