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一例脑积水手术后分流堵塞所致精神障碍的病例报告。

A case report of mental disorder caused by shunt blockage after hydrocephalus surgery.

作者信息

Wu Jingjing, Li Wei, Wang Yaping, Liu Lijin, Liu Lanying

机构信息

Department of Traditional Chinese Medicine, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Xuzhou Oriental Hospital, Xuzhou Medical University, Xuzhou, China.

出版信息

Front Psychiatry. 2024 Dec 4;15:1503993. doi: 10.3389/fpsyt.2024.1503993. eCollection 2024.

Abstract

INTRODUCTION

Hydrocephalus is a form of communication hydrocephalus syndrome characterized by ventricular enlargement and normal intraventricular pressure. The primary clinical manifestations include gait disturbances, cognitive dysfunction, urinary incontinence, and either elevated or normal intracranial pressure. This paper presents a case of a mental disorder resulting from inadequate drainage following a ventriculoperitoneal shunt procedure for hydrocephalus. The case report aims to enhance clinicians' understanding of such organic brain lesions, which are prone to misdiagnosis and inappropriate treatment, thereby improving differential diagnostic skills.

CASE PRESENTATION

This case report describes a 34-year-old male with a 16-year history of depressive disorder, previously managed with 150 mg of venlafaxine daily, 7.5 mg of zopiclone every night, and 2.4 g of piracetam every day. The patient underwent a ventriculoperitoneal shunt procedure for hydrocephalus, leading to the development of a mental disorder attributable to poor drainage from the shunt tube. Initial symptoms consisted of low mood, decreased interest, and cognitive impairment. Despite psychiatric consultation and antidepressant treatment, there was no improvement in his condition. The final diagnosis was an organic mental disorder. Following an increase in shunt drainage and the administration of a low dose of olanzapine, the patient's psychiatric symptoms showed significant improvement.

CONCLUSION

Reporting this case seeks to enhance clinicians' awareness of the psychiatric manifestations of organic brain lesions, expand the differential diagnostic approach for psychiatrists, and improve diagnostic accuracy. Additionally, it emphasizes the need for cautious use of psychiatric medications, appropriate symptomatic management, and timely referral when necessary.

摘要

引言

脑积水是交通性脑积水综合征的一种形式,其特征为脑室扩大和脑室内压力正常。主要临床表现包括步态障碍、认知功能障碍、尿失禁以及颅内压升高或正常。本文介绍了一例因脑积水脑室腹腔分流术后引流不足导致精神障碍的病例。该病例报告旨在增强临床医生对这类易被误诊和治疗不当的器质性脑损伤的认识,从而提高鉴别诊断能力。

病例介绍

本病例报告描述了一名34岁男性,有16年抑郁症病史,此前每日服用150毫克文拉法辛、每晚服用7.5毫克佐匹克隆以及每天服用2.4克吡拉西坦进行治疗。该患者因脑积水接受了脑室腹腔分流术,导致因分流管引流不畅而出现精神障碍。初始症状包括情绪低落、兴趣减退和认知障碍。尽管进行了精神科会诊并给予抗抑郁治疗,但其病情并无改善。最终诊断为器质性精神障碍。在增加分流管引流量并给予低剂量奥氮平后,患者的精神症状有了显著改善。

结论

报告此病例旨在提高临床医生对器质性脑损伤精神表现的认识,拓宽精神科医生的鉴别诊断方法,提高诊断准确性。此外,强调了谨慎使用精神科药物、进行适当的对症处理以及在必要时及时转诊的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/937d/11652516/65c2bf2f46d2/fpsyt-15-1503993-g001.jpg

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