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撤回声明:KCNQ1OT1对RUNX3的甲基化依赖性转录抑制调节心肌梗死后小鼠心脏微血管内皮细胞的活力和炎症反应。

RETRACTION: Methylation-Dependent Transcriptional Repression of RUNX3 by KCNQ1OT1 Regulates Mouse Cardiac Microvascular Endothelial Cell Viability and Inflammatory Response Following Myocardial Infarction.

出版信息

FASEB J. 2024 Dec 13;38(24):e70209. doi: 10.1096/fsb2.70209.

DOI:10.1096/fsb2.70209
PMID:39698910
Abstract

Y. Wang, X. Yang, A. Jiang, W. Wang, J. Li, and J. Wen, "Methylation-Dependent Transcriptional Repression of RUNX3 by KCNQ1OT1 Regulates Mouse Cardiac Microvascular Endothelial Cell Viability and Inflammatory Response Following Myocardial Infarction," FASEB Journal 33, no. 12 (2019): 13145-13160. https://doi.org/10.1096/fj.201900310R. The above article, published online on 18 October 2019, in Wiley Online Library (wileyonlinelibrary.com), has been retracted by agreement between the journal Editor-in-Chief, Dr. Loren E. Wold, the Federation of American Societies for Experimental Biology, and Wiley Periodicals LLC. The authors contacted the journal and requested withdrawal of their article due to incorrect data. Further investigation of the article by the publisher found that Figure 3D in this article was duplicated from other articles by different author groups, in which each was used in a different scientific context. Additionally, concerns have been raised by a third party regarding the veracity of the data expressed in Figures 2F, 3I, 5H, and 6H. The retraction has been agreed to because the evidence of image duplication across different articles, each of which describes different experimental conditions, fundamentally compromises the editors' confidence in the conclusions presented. The authors did not respond to our notice regarding the retraction.

摘要

王Y、杨X、姜A、王W、李J和温J,“KCNQ1OT1对RUNX3的甲基化依赖性转录抑制调节小鼠心肌梗死后心脏微血管内皮细胞活力和炎症反应”,《美国实验生物学学会联合会会刊》33卷,第12期(2019年):13145 - 13160页。https://doi.org/10.1096/fj.201900310R。上述文章于2019年10月18日在线发表于威利在线图书馆(wileyonlinelibrary.com),经该期刊主编洛伦·E·沃尔德博士、美国实验生物学学会联合会以及威利期刊有限责任公司协商一致后予以撤稿。作者联系期刊并因数据错误请求撤回其文章。出版商对该文章进一步调查发现,本文图3D系复制自不同作者团队的其他文章,且每张图用于不同的科学背景。此外,第三方对图2F、3I、5H和6H中所表达数据的真实性提出了质疑。之所以同意撤稿,是因为不同文章(每篇文章描述不同实验条件)间存在图像复制的证据,从根本上损害了编辑对所呈现结论的信心。作者未对我们关于撤稿的通知做出回应。

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