Frazier Thomas W, Dimitropoulos Anastasia, Abbeduto Leonard, Armstrong-Brine Melissa, Kralovic Shanna, Shih Andy, Hardan Antonio Y, Youngstrom Eric A, Uljarević Mirko
Department of Psychology, John Carroll University, University Heights, OH, USA.
Department of Pediatrics, SUNY Upstate Medical University, Syracuse, NY, USA.
Dev Med Child Neurol. 2025 Jun;67(6):758-769. doi: 10.1111/dmcn.16200. Epub 2024 Dec 19.
To replicate and extend previous psychometric findings for the Autism Symptom Dimensions Questionnaire (ASDQ).
Using a cross-sectional design in two samples, including a total of 3366 children and adolescents (aged 2-17 years; 1399 with autism spectrum disorder) and a small case series, factor structure, measurement invariance, reliability, construct validity, screening and diagnostic efficiency, and detection of reliable change were examined for the ASDQ.
Strong psychometric properties were observed, including replicable factor structure, strong measurement invariance, adequate-to-excellent scale and conditional reliability, strong convergent and discriminant validity, and good screening efficiency. Importantly, two crucial measurement aspects required for a good treatment outcome measure were found, that is, good test-retest stability and the potential to detect reliable change. As expected for an informant-reported questionnaire, diagnostic efficiency was weak.
The ASDQ showed evidence of favorable and well-replicated psychometric properties in two samples. Good screening but weak diagnostic efficiency, coupled with good test-retest stability, suggest that optimal clinical use is in screening and in detailed clinical characterization beyond what is offered by current informant-reported measures, with the potential for monitoring response to intervention. Despite relative brevity, the ASDQ provides good coverage of broad and specific aspects of the autism behavioral phenotype, which is consistent with the criteria of the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition.
复制并扩展先前关于自闭症症状维度问卷（ASDQ）的心理测量学研究结果。
采用横断面设计，对两个样本进行研究，样本包括总共3366名儿童和青少年（年龄在2至17岁之间；1399名患有自闭症谱系障碍）以及一个小病例系列，对ASDQ的因子结构、测量不变性、信度、结构效度、筛查和诊断效率以及可靠变化的检测进行了检验。
观察到了强大的心理测量学特性，包括可复制的因子结构、强大的测量不变性、足够到优秀的量表和条件信度、强大的收敛效度和区分效度以及良好的筛查效率。重要的是，发现了良好治疗结果测量所需的两个关键测量方面，即良好的重测稳定性和检测可靠变化的潜力。正如预期的那样，对于一份由知情者报告的问卷，诊断效率较弱。
ASDQ在两个样本中显示出具有良好且可重复的心理测量学特性的证据。良好的筛查但较弱的诊断效率，再加上良好的重测稳定性，表明其最佳临床用途在于筛查以及提供超出当前知情者报告测量所能提供的详细临床特征，并且有可能监测对干预的反应。尽管相对简短，但ASDQ对自闭症行为表型的广泛和具体方面提供了良好的覆盖，这与《精神疾病诊断与统计手册》第五版的标准一致。
