Wang Zhunan, Zhang Liyu, Liu Xin, Xu Lan
Department of gynaecology, Gynecological Diagnosis and Treatment Center, Affliated Hospital of Changchun University of Chinese Medicine, No.2, Shenzhen Street, Changchun city, Jilin Province 130000, China.
Department of gynaecology and obstetrics, Gynecological Diagnosis and Treatment Center, Affliated Hospital of Changchun University of Chinese Medicine, No.2, Shenzhen Street, Changchun city, Jilin Province 130000, China.
J Reprod Immunol. 2025 Feb;167:104418. doi: 10.1016/j.jri.2024.104418. Epub 2024 Dec 15.
The reproductive tract, as a lumen connected to the outside world, its microbial community is influenced by various factors. The changes in its microbiome are closely related to women's health. The destruction of the micro ecological environment will lead to various infections, such as Bacterial vaginosis, sexually transmitted infections, adverse pregnancy outcomes, infertility and tumors. In recent years, with the continuous development and progress of molecular biology, research on reproductive tract microbiota has become a clinical hotspot. The reproductive tract microbiota is closely related to the occurrence and development of female reproductive tract diseases such as vaginitis, pelvic inflammation, PCOS, cervical lesions, and malignant tumors. This article reviews the research on the relationship between vaginal microbiota and female reproductive tract diseases, in order to provide theoretical basis for the prevention and treatment of female reproductive tract diseases.
生殖道作为一个与外界相通的管腔，其微生物群落受到多种因素的影响。其微生物组的变化与女性健康密切相关。微生态环境的破坏会导致各种感染，如细菌性阴道病、性传播感染、不良妊娠结局、不孕和肿瘤。近年来，随着分子生物学的不断发展和进步，生殖道微生物群的研究已成为临床热点。生殖道微生物群与阴道炎、盆腔炎、多囊卵巢综合征、宫颈病变和恶性肿瘤等女性生殖道疾病的发生发展密切相关。本文综述了阴道微生物群与女性生殖道疾病关系的研究，旨在为女性生殖道疾病的防治提供理论依据。
