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接受心脏手术的儿科患者发生脑空气栓塞

Cerebral air embolism in pediatric patients undergoing cardiac surgery.

作者信息

Hubara Evyatar, Feingold Iris Motro, Skourikhin Yelena, Lerner Reut Kassif, Vardi Amir, Mishaly David, Katz Uriel, Bar-Yosef Omer

机构信息

Pediatric Intensive Care Unit, The Edmond and Lily Safra Children's Hospital, Sheba Medical Center, Tel Hashomer, Israel.

The Department for Pediatric Cardiac Critical Care Medicine, The Edmond and Lily Safra Children's Hospital, Sheba Derech Sheba 2, Ramat Gan, Israel.

出版信息

J Cardiothorac Surg. 2024 Dec 19;19(1):655. doi: 10.1186/s13019-024-03152-5.

DOI:10.1186/s13019-024-03152-5
PMID:39702304
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11661006/
Abstract

OBJECTIVE

Cerebral air embolism during Cardio-Pulmonary Bypass is a severe complication with significant neurological risks. We present six pediatric cases, detailing their presentation, management, and outcomes. The discussion reviews existing literature and proposes management guidelines for suspected air emboli.

METHODS

A Case Series Report. A retrospective review of medical records was conducted to identify pediatric patients who experienced cerebral air embolism during cardiac surgeries with CPB between January 2009 to December 2023.

MAIN FINDINGS

Throughout the study duration, six patients experienced cerebral air emboli as a complication of their cardiac surgeries. Patients' ages ranged from 8 months to 16 years, with five having single ventricle physiology. Tear-induced cerebral air emboli from right atrium dissection were observed in five cases. Seizures following surgery were the predominant clinical manifestation. Neurological outcomes varied; three patients showed minimal deficits at discharge, while other three cases suffered significant damage leading to substantial deficits.

CONCLUSIONS

We present a case series documenting the occurrence of a rare complication-cerebral air emboli-during cardiac surgery in children. Our study highlight a spectrum of neurological outcomes in affected patients and provides guidelines for the identification and treatment of this complication.

摘要

目的

体外循环期间发生的脑空气栓塞是一种严重并发症,具有重大的神经学风险。我们报告六例儿科病例,详细阐述其临床表现、治疗及预后情况。讨论回顾了现有文献,并提出了疑似空气栓塞的管理指南。

方法

病例系列报告。对2009年1月至2023年12月期间在心脏手术体外循环过程中发生脑空气栓塞的儿科患者的病历进行回顾性研究。

主要发现

在整个研究期间,六例患者在心脏手术中发生脑空气栓塞并发症。患者年龄从8个月至16岁不等,其中五例为单心室生理状态。五例观察到因右心房解剖撕裂导致的脑空气栓塞。术后癫痫发作是主要临床表现。神经学预后各不相同;三名患者出院时仅有轻微功能缺损,而其他三例则遭受严重损伤导致明显功能障碍。

结论

我们报告了一个病例系列,记录了儿童心脏手术期间发生的一种罕见并发症——脑空气栓塞。我们的研究突出了受影响患者的一系列神经学预后情况,并为该并发症的识别和治疗提供了指南。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cd/11661006/25be3d6f78f1/13019_2024_3152_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cd/11661006/72149047fb82/13019_2024_3152_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cd/11661006/25be3d6f78f1/13019_2024_3152_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cd/11661006/72149047fb82/13019_2024_3152_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/92cd/11661006/25be3d6f78f1/13019_2024_3152_Fig2_HTML.jpg

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Early hyperbaric oxygen therapy is associated with favorable outcome in patients with iatrogenic cerebral arterial gas embolism: systematic review and individual patient data meta-analysis of observational studies.早期高压氧治疗与医源性脑动脉气体栓塞患者的良好转归相关:观察性研究的系统评价和个体患者数据分析荟萃分析。
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