不明原因的致残性持续性咳嗽：一例报告
Unexplained disabling and long-lasting cough: a case report.
作者信息
Ferrante Francesco, Onorati Ilaria, Radu Dana Mihaela, Herve-Carrega Aurélie, Didier Morgane, Huet Olivier, Martinod Emmanuel
机构信息
Chirurgie Thoracique et Vasculaire, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Seine-Saint-Denis, Hôpital Avicenne, Université Sorbonne Paris Nord, Bobigny, France.
Pneumologie, Assistance Publique-Hôpitaux de Paris, Hôpitaux Universitaires Paris Seine-Saint-Denis, Hôpital Avicenne, Université Sorbonne Paris Nord, Bobigny, France.
出版信息
J Cardiothorac Surg. 2024 Dec 19;19(1):648. doi: 10.1186/s13019-024-03189-6.
BACKGROUND
A 51-year-old woman was referred to our department due to chronic dry cough lasting six years without an etiological diagnosis. The patient suffered from chronic deterioration in her quality of life due to a persistent cough that sounded like a barking seal.
CASE PRESENTATION
A severe form of malacia involving the inferior third of trachea and the main bronchi was diagnosed. According to our protocol, a self-expandable prothesis was placed in the distal portion of the trachea via rigid bronchoscopy with excellent results in cough relief. The patient was subsequently scheduled for tracheobronchoplastic surgery with a polypropylene matrix. Two and a half years after surgery the patient had a significant improvement in quality of life with a complete resolution of her symptoms.
CONCLUSION
This report demonstrated that tracheobronchomalacia can be difficult to diagnose with a serious impact on the patient's life. Referral to a specialized center is essential in the diagnostic and therapeutic management of this disease. Surgical treatment by tracheobronchoplasty may represent a good solution in selected patients.
背景
一名51岁女性因持续六年的慢性干咳且病因未明被转诊至我科。由于持续咳嗽声如海豹吠叫，患者生活质量长期恶化。
病例介绍
诊断为累及气管下三分之一及主支气管的严重软化症。根据我们的方案，通过硬质支气管镜在气管远端置入自膨式假体，在缓解咳嗽方面效果极佳。患者随后被安排进行聚丙烯基质的气管支气管成形手术。术后两年半，患者生活质量显著改善，症状完全消失。
结论
本报告表明气管支气管软化症可能难以诊断，对患者生活有严重影响。转诊至专业中心对该病的诊断和治疗管理至关重要。气管支气管成形术的手术治疗可能是部分患者的良好解决方案。
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