Adnan Shanza, Farrukh Saba, Ahmed Arsalan, Shaikh Muhammad Shariq
Department of Pathology and Laboratory Medicine, Aga Khan University, Karachi, Pakistan.
Int J Hematol Oncol Stem Cell Res. 2024 Oct 1;18(4):400-402. doi: 10.18502/ijhoscr.v18i4.16764.
Hairy cell leukemia (HCL) is a rare B-cell neoplasm that constitutes around 2 percent of all lymphoid leukemias and occurs more frequently in elderly males. The usual triad of HCL includes pancytopenia, splenomegaly, and hairy cells in the bone marrow. This is a case of an atypical presentation of biclonal HCL diagnosed on flow cytometry; the existence of biclonal HCL is extremely rare with very few case reports. Pure biclonal HCL should be regarded as an extraordinary finding among the so-called composite lymphomas.
毛细胞白血病（HCL）是一种罕见的B细胞肿瘤，约占所有淋巴细胞白血病的2%，在老年男性中更常见。HCL通常的三联征包括全血细胞减少、脾肿大和骨髓中的毛细胞。这是一例通过流式细胞术诊断的双克隆HCL非典型表现病例；双克隆HCL的存在极为罕见，仅有极少病例报告。纯双克隆HCL应被视为所谓复合淋巴瘤中的一种特殊发现。
