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儿童哮喘中哭泣诱发的支气管痉挛:对药物治疗的反应

Crying-induced bronchospasm in childhood asthma: response to medical management.

作者信息

Weinstein A G

出版信息

Ann Allergy. 1985 Feb;54(2):105-8.

PMID:3970387
Abstract

Crying-induced bronchospasm (CIB), cough and/or wheeze greater than or equal to 5 minutes during or after crying behavior, is a common feature of childhood asthma. Sixty CIB patients were evaluated during a 6-month clinical treatment study consisting of environmental and pharmacologic (xanthines, beta-agonist stimulants, and corticosteroids) interventions. Both CIB (P = .007) and non-CIB (P = .0005) symptoms were significantly reduced. CIB asthma had lesser reduction in wheezing than non-CIB (P less than .001), suggesting that nebulized medication and/or behavioral interventions may be of benefit to further reduce CIB symptoms.

摘要

哭泣诱发的支气管痉挛(CIB),即在哭泣行为期间或之后咳嗽和/或喘息大于或等于5分钟,是儿童哮喘的常见特征。在一项为期6个月的临床治疗研究中,对60名CIB患者进行了评估,该研究包括环境和药物(黄嘌呤、β-激动剂兴奋剂和皮质类固醇)干预。CIB(P = 0.007)和非CIB(P = 0.0005)症状均显著减轻。CIB哮喘患者喘息的减轻程度低于非CIB患者(P小于0.001),这表明雾化药物和/或行为干预可能有助于进一步减轻CIB症状。

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